DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and Olfr112

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_001013593.2	Gene:	Olfr112 / 258096	MGIID:	2177495	Length:	320	Species:	Mus musculus

Alignment Length:	339	Identity:	68/339 - (20%)
Similarity:	128/339 - (37%)	Gaps:	86/339 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 LPLYKAVLITIIFGGIFITGVVGNLLVCIVIIRHSAMHTATNYYLFSLAVSDLLYLLFGLPTEVF 127
            |.:.:|||..:    .::.|..||:::..:......:.:...|:|..|::.||..|...:|
Mouse    23 LQIVQAVLFLV----TYLVGSAGNVIIITITTLDPQLQSPMYYFLKHLSILDLSSLSVTVP---- 79

  Fly   128 LYWHQYPD-------LFGMPFCKIRAFISEACTYVSVFTIVAFSMERFLAICHPLHLYAMVGFKR 185
                ||.|       ......|.::.|...|..:..:..:...|.:|::|||.|||...::..::
Mouse    80 ----QYVDSSLAQSGYISYAQCMLQIFFFTAFAWGELAILTVMSYDRYVAICLPLHYEVIMSPRK 140

  Fly   186 AIRIITALWIVSFISAIPFGLLSDIQYLNYPLDHSRIEESAFCSMSPKIV------NEIPVFE-- 242
            ....:..:|:...||...:  ::...::.:..|  :|....||.: |:::      :.:.:.:
Mouse   141 CTWAVATVWLSGGISGTLY--ITGTLFIRFCGD--KIIHQFFCDV-PQLLKLSCSNDHLVIMDMV 200

  Fly   243 -----VSFCIF--FVIPMILIILLYGRM-GAKIRSRTNQKLGVQQGTNNRETRNSQMRKKTVIRM 299
                 |||..|  .||..:.|.....|| .|:.||:
Mouse   201 SFLTAVSFACFTGIVISYVHIFSTVLRMPSAESRSK----------------------------- 236

  Fly   300 LAAVVITFFVCWFPFHLQRLIFLYAKNMDNYLDIN-------EALFSIAGFAYYVSCTVNPIVYS 357
                  .|..| .| ||..:....:.....||::.       |.|.||  |...:..|:||::||
Mouse   237 ------VFSTC-LP-HLFVVSLFLSTGAFAYLNLTSDSSTALEFLLSI--FYTVLPPTLNPVIYS 291

  Fly   358 VMSRRYRVAFRELL 371
            :.:...:...|:||
Mouse   292 LRNETIKNVVRKLL 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	63/317 (20%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	58/300 (19%)
Olfr112	NP_001013593.2	7tmA_OR14-like	25..294	CDD:320355	64/324 (20%)
		TM helix 1	26..52	CDD:320355	6/29 (21%)
		TM helix 2	59..85	CDD:320355	10/33 (30%)
		TM helix 3	97..127	CDD:320355	6/29 (21%)
		TM helix 4	139..160	CDD:320355	3/22 (14%)
		TM helix 5	195..225	CDD:320355	7/29 (24%)
		TM helix 6	232..262	CDD:320355	9/66 (14%)
		TM helix 7	269..294	CDD:320355	10/26 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000