DRSC/TRiP Functional Genomics Resources

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Protein Alignment CapaR and NTSR2

DIOPT Version :9

Sequence 1:NP_996140.1 Gene:CapaR / 40393 FlyBaseID:FBgn0037100 Length:477 Species:Drosophila melanogaster
Sequence 2:NP_036476.2 Gene:NTSR2 / 23620 HGNCID:8040 Length:410 Species:Homo sapiens


Alignment Length:362 Identity:93/362 - (25%)
Similarity:168/362 - (46%) Gaps:50/362 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    58 LGPQTLPLYKAVLITIIFGGIFITGVVGNLLVCIVIIRHSAMHTA-TNYYLFSLAVSDLLYLLFG 121
            ||..| .|:..||.|.::..|:..|..||.|...|:::..|.... ..:::.|||::.||.||.|
Human    23 LGVDT-RLWAKVLFTALYALIWALGAAGNALSAHVVLKARAGRAGRLRHHVLSLALAGLLLLLVG 86

  Fly   122 LPTEVFLY-WHQYPDLFGMPFCKIRAFISEACTYVSVFTIVAFSMERFLAICHPLHLYAMVGFKR 185
            :|.|::.: |..||.:||...|:...|:.|.|.|.:|.::...|.||.||:|.||...:::..:|
Human    87 VPVELYSFVWFHYPWVFGDLGCRGYYFVHELCAYATVLSVAGLSAERCLAVCQPLRARSLLTPRR 151

  Fly   186 AIRIITALWIVSFISAIPFGLLSDIQYLNYPLDHSRIEESAFCSMSPKIVNE--IPVF-EVSFCI 247
            ...::...|..|...|:|..::...::.....|......|..|::   :|:.  :.|| :|:..:
Human   152 TRWLVALSWAASLGLALPMAVIMGQKHELETADGEPEPASRVCTV---LVSRTALQVFIQVNVLV 213

  Fly   248 FFVIPMILIILLYG-----------------RMGAKIRSRTN-------------QKLGVQQG-- 280
            .||:|:.|...|.|                 ..|:...||..             :|..:|.|  
Human   214 SFVLPLALTAFLNGVTVSHLLALCSQVPSTSTPGSSTPSRLELLSEEGLLSFIVWKKTFIQGGQV 278

  Fly   281 --TNNRETRNSQMRKKTVIRMLAAVVITFFVCWFPFHLQRLIFLYAKN---MDNYLDINEALFSI 340
              ..:::.|..:..:::| ::|.|:|:.:.:||.|:|.:||::.|..:   .|...:.....:.:
Human   279 SLVRHKDVRRIRSLQRSV-QVLRAIVVMYVICWLPYHARRLMYCYVPDDAWTDPLYNFYHYFYMV 342

  Fly   341 AGFAYYVSCTVNPIVYSVMSRRYRVAFREL---LCGK 374
            ....:|||..|.|::|:.:|..:|..|.|.   |||:
Human   343 TNTLFYVSSAVTPLLYNAVSSSFRKLFLEAVSSLCGE 379

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CapaRNP_996140.1 7tm_4 85..374 CDD:304433 83/333 (25%)
7tm_1 85..356 CDD:278431 76/312 (24%)
NTSR2NP_036476.2 7tmA_NTSR2 33..369 CDD:320478 84/339 (25%)
TM helix 1 33..60 CDD:320478 9/26 (35%)
TM helix 2 68..94 CDD:320478 10/25 (40%)
TM helix 3 108..138 CDD:320478 11/29 (38%)
TM helix 4 152..170 CDD:320478 3/17 (18%)
TM helix 5 203..232 CDD:320478 9/28 (32%)
TM helix 6 290..320 CDD:320478 10/30 (33%)
TM helix 7 337..362 CDD:320478 6/24 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 381..410
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D380940at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24243
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
33.020

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