DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and srw-109

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_503261.2	Gene:	srw-109 / 191334	WormBaseID:	WBGene00005856	Length:	357	Species:	Caenorhabditis elegans

Alignment Length:	366	Identity:	58/366 - (15%)
Similarity:	120/366 - (32%)	Gaps:	139/366 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 FITGVVG---NLLVCIVIIRHSAMHTATNYYLFSLAVSDLLYLLFGLPTEVFLYWH----QYPDL 136
            ||..::.   |||..::|.|.|...::.|..:..:.|.|:..:|    |.::.|..    :||:.
Worm    29 FILAIISFILNLLHFVIITRKSIRISSINCLMVGVTVCDICRML----TTIYRYLELEDLEYPEC 89

  Fly   137 FGMPFCKIRAFISEACTYVSVF-TIVAFSMERFLAICHPLHLYAMVGFKRAIRIITALWIVSFIS 200
            .            ...:|:..: .|.::.::.:...|                   :.|:..||:
Worm    90 I------------TVSSYIKAYLDITSWWLQDYFRRC-------------------SSWLDIFIA 123

  Fly   201 AIPFGLLSDIQYLNYPLDHSRIEES------------------AFCSMSPKIVNEIPVFEVSFC- 246
            .:.:.::..:....    :|:..:|                  :.|..|.:||.:..:|..|.|
Worm   124 NVRYIIMRKVSGAR----NSKTAQSKLGFILMTLVFCTSNLIQSMCLYSIQIVEKRDIFLFSNCA 184

  Fly   247 ------------------------------IFF-----------VIPMILIILLYGRMGAKIRSR 270
                                          ||.           ..|::.::||     .||:..
Worm   185 EHQDINKVYKYTINLRPIPTDNKMLLIRTYIFLDVIFSHFLPSQAFPILTVLLL-----RKIQKM 244

  Fly   271 TNQKLGVQQGTNNRETRNSQMRKKTVIRMLAAVVITFFVC------------WFPFHLQRLIFLY 323
            ...:..|:   |||...|::.:......::..:.|:.|:.            :.|...:|:.||
Worm   245 EKSRPVVR---NNRVAENNEDKHPLSTNLIIFLTISSFLADAPLGCIVMIKLFIPSGNRRIRFL- 305

  Fly   324 AKNMDNYLDINEALFSIAGFAYYVSCTVNPIVYSVMSRRYR 364
             .::..||:|...:..:          ..||:...|.|:||
Worm   306 -TDLIVYLNILSTIIIM----------FRPILCFSMPRQYR 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	56/360 (16%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	52/350 (15%)
srw-109	NP_503261.2	TM helix 1	26..49	CDD:341315	6/19 (32%)
		7TM_GPCR_Srw	27..345	CDD:370978	58/366 (16%)
		TM helix 2	56..81	CDD:341315	6/28 (21%)
		TM helix 3	101..131	CDD:341315	5/48 (10%)
		TM helix 4	145..165	CDD:341315	0/19 (0%)
		TM helix 5	211..236	CDD:341315	3/24 (13%)
		TM helix 6	262..293	CDD:341315	2/30 (7%)
		TM helix 7	306..331	CDD:341315	5/34 (15%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910