DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and srw-82

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_001346696.1	Gene:	srw-82 / 191269	WormBaseID:	WBGene00005829	Length:	353	Species:	Caenorhabditis elegans

Alignment Length:	351	Identity:	66/351 - (18%)
Similarity:	118/351 - (33%)	Gaps:	98/351 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 FITGVVGNLLVC--IVIIRHSAMHT-ATNYYLFSLAVSDLLYLLFGLPTEVFLYW---------H 131
            |:..::..|:..  :.|:..::|.| :||..:..::::||:.|...:.....|||         :
Worm    27 FVVAILALLMNIPHLFILTRTSMRTHSTNSLMIGISIADLISLFMMINNRAQLYWLSPNTCFNSY 91

  Fly   132 QYP--------DL-----------FGMPFCKIRAFISE---------ACTYVSVFTIVAFSMERF 168
            .||        |:           .|:....||..|.:         :.|....|..:.|.....
Worm    92 TYPLNVARFVQDVSWESMMRVSFYLGLCLALIRCIIMKMSGNAPDILSTTRNGYFLTLFFIFVNT 156

  Fly   169 LAICHPLHLYAMVGFKRAIRIITALWIVSFISAIPFGLLSDIQYLNYPLDHSRIEESAFCSMSPK 233
            |..|...:.:.::.:|..       |            ...:....:|   ::..|..|.....|
Worm   157 LISCFYYYGFRVIKYKEP-------W------------TPGVNCTGFP---AKYREPYFYRAPKK 199

  Fly   234 IVNEIPVFEVSFCIFFVIPMILIILLYGRMGAKIRSRTNQKLGVQQGTNNRETRNSQMRKKTVI- 297
              |::...| .:.||.....|||..||...|.         |.:.:...:.:...:.:.||..:
Worm   200 --NQLFTSE-RYEIFTGCSDILIAALYPIFGL---------LLMLEVLKSAKVAATMLSKKDAVE 252

  Fly   298 -----RMLAAVVITFFVCWFPFHLQRLI--FLYAK-NMDNYLDINEALFSIAGFAY--------Y 346
                 ||:..:.|.:....||....:::  |.|.. ..|.|..:   :|:..|..:        .
Worm   253 RYHTSRMILVMTIFYIFASFPTGAYKIVNFFFYESWRKDGYFYV---VFTYTGKIFTSLFCGNAL 314

  Fly   347 VSCTVNPIVYSVMSRRYRVAFRELLC 372
            ..|.:|    ..|||.||.|..||.|
Worm   315 SHCLIN----LSMSRNYRNAVMELGC 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	65/345 (19%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	56/327 (17%)
srw-82	NP_001346696.1	7TM_GPCR_Srw	24..337	CDD:370978	66/351 (19%)
		TM helix 1	25..47	CDD:341315	3/19 (16%)
		TM helix 2	54..84	CDD:341315	8/29 (28%)
		TM helix 3	99..129	CDD:341315	5/29 (17%)
		TM helix 4	141..159	CDD:341315	4/17 (24%)
		TM helix 5	194..229	CDD:341315	11/46 (24%)
		TM helix 6	256..281	CDD:341315	5/24 (21%)
		TM helix 7	296..324	CDD:341315	4/34 (12%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910