DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and srw-1

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_506753.2	Gene:	srw-1 / 190719	WormBaseID:	WBGene00005748	Length:	349	Species:	Caenorhabditis elegans

Alignment Length:	368	Identity:	73/368 - (19%)
Similarity:	136/368 - (36%)	Gaps:	94/368 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 YKAVLITIIFGGIFITGVVGNLLVCIVIIRHSAMHTATNYYLFSLAVSDLLYLLFGLPTEV-FLY 129
            |.|.|:..:   |...|::.|:....::||.|...:.....:|.:.:.|||.||.....:: ::.
Worm    16 YHARLVNTV---ISFLGLLSNIFHFSILIRKSLRSSPVFSMMFVICICDLLQLLTQTQNDIKYIL 77

  Fly   130 WHQYPDLFGMPFC-KIRAFISEACTYVSVFTIVAFSMERFLAICHPLHLYAMVGFKRAIRIITAL 193
            ....||     || ....:.:.|.| :::.|:..|||  .::.|    |..:|...|::.|..|:
Worm    78 EFNQPD-----FCLGFDTYYATALT-LTMETLGGFSM--LVSSC----LVILVALFRSLSIKFAM 130

  Fly   194 --W---------------IVSFISAIPFGLLSDIQYLNYPLDHSRIE-----ESAFCSMS----- 231
              |               ||..|||:          .|....|.:.:     :.|||:.|
Worm   131 SKWSSTLAKTSTARKTSLIVIIISAM----------YNLSATHFKYKITPKSDDAFCAFSFYTGA 185

  Fly   232 ------------PKIVNEI---PVFEVSFCIFFVIPMILIILLYGRMGAKIRSRTNQKLGVQQGT 281
                        ....|.|   .:|:....||.:|..|...|:..|.   |:..::.|:
Worm   186 SSERRLYSASDGHSSTNAILLFTLFDGLIQIFQLIVFIFTSLILSRF---IKEASSMKM------ 241

  Fly   282 NNRETRNSQMRKKTVIRMLAAVVITFFVCWFPFHLQRLIFLYAKNMDNYLDINEALFSIAGFAYY 346
              .::::.:..:||. .::...:.:||:..||..:...:.....|:.....|.....:|:.....
Worm   242 --MKSKSDRQAEKTE-GLILFTLCSFFISTFPIIIANFMLPLFANLQIIPLILIRTLTISTMLQT 303

  Fly   347 VSCTVNPIVYSVMSRRYRVAFRELLCGKAVGAYYNSGFARDHS 389
            ::...:..|..:||.:||             |...:.|:.|||
Worm   304 INAATHGWVCLLMSSQYR-------------AVAKTAFSPDHS 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	63/332 (19%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	58/314 (18%)
srw-1	NP_506753.2	7tm_GPCRs	21..329	CDD:391938	66/357 (18%)
		TM helix 2	50..79	CDD:341315	6/28 (21%)
		TM helix 3	97..127	CDD:341315	9/36 (25%)
		TM helix 4	141..162	CDD:341315	6/30 (20%)
		TM helix 5	204..227	CDD:341315	6/22 (27%)
		TM helix 6	248..278	CDD:341315	6/30 (20%)
		TM helix 7	291..317	CDD:341315	2/25 (8%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910