DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and srw-84

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_507772.1	Gene:	srw-84 / 189867	WormBaseID:	WBGene00005831	Length:	369	Species:	Caenorhabditis elegans

Alignment Length:	417	Identity:	92/417 - (22%)
Similarity:	161/417 - (38%)	Gaps:	136/417 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 PKEFVAF----VLGPQTLPLYKAVL-ITIIFGGIFITGVVGNLLVCIVIIRHSAMHTATNYYLFS 109
            |:||..|    :...|...::.:.| |.:.|.|:|.     |:|...:::..|....|||..:..
Worm    12 PQEFQQFLRNLLQNSQNWAVFCSNLQIFMSFFGVFF-----NILHIFILLNKSMRRQATNVLIIG 71

  Fly   110 LAVSDLLYLLF------------GLP-------TEVFLYWHQYPDLFGMPFCKIRAFISEACTYV 155
            :|:||:.||.:            |:|       ||...|:.....:|...|.:           |
Worm    72 IAISDIFYLFYYVEGGTREFLENGIPGKCRPKKTEFLAYYIWIVTIFKDVFRR-----------V 125

  Fly   156 SVFTIVAFSMERFLAICHPLHLYAMVGFKRAIRI---ITALWIVSFISAIPFGL-LSDIQYLNY- 215
            |.|:.|:.::.|:|.:.:        |.:..||:   .:..|.: |.|.|.|.| :|.|.::.|
Worm   126 SAFSGVSLALIRYLVMKY--------GARTNIRVYVTTSTSWAL-FFSTILFSLVISSINHVRYI 181

  Fly   216 --------PLDHSRIEESAFCSMSPKIVNEIPVFE---------------VSFC----IFFVIPM 253
                    |      .||  |.|.|.... :|.||               ..|.    :|.:||.
Worm   182 VMRYPDWVP------PES--CKMYPPNTT-LPWFEQVQNPDLGDFQRQISTKFLYIDGVFKIIPP 237

  Fly   254 ILI-ILLYGRMGAKIRSRTNQKLGVQQGTNNRETRNSQMRKKTVIRMLAAVVITFFVCWFP---- 313
            ||. .|.:|.:....::|.::|:.:::|..:....        |.:::..:.|.:|:...|
Worm   238 ILYPFLAFGLLWELKKARDSRKILMRKGEEHEMVH--------VTKLVIFMTIGYFLAETPVGIS 294

  Fly   314 -FHLQ-------RLIFLYAKNMD----NYLDINEALFSIAGFAYYVSCTVNPIVYSVMSRRYRVA 366
             |:|.       .:||| |.|:.    .:|.||.::...  |.::            :|.:||:|
Worm   295 YFYLAYNMGEDFGIIFL-ANNITVIFVTFLIINSSIHCF--FCFF------------LSSQYRLA 344

  Fly   367 FRELL---CGKAVGAYYNSGFARDHSS 390
            |..:.   |..:..:..||   |:.||
Worm   345 FWSIFGCKCASSGSSVSNS---RNMSS 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	77/359 (21%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	71/338 (21%)
srw-84	NP_507772.1	TM helix 1	32..58	CDD:341315	7/30 (23%)
		7TM_GPCR_Srw	35..352	CDD:370978	81/373 (22%)
		TM helix 2	65..94	CDD:341315	7/28 (25%)
		TM helix 3	112..142	CDD:341315	8/40 (20%)
		TM helix 4	156..176	CDD:341315	7/20 (35%)
		TM helix 5	220..246	CDD:341315	7/25 (28%)
		TM helix 6	273..298	CDD:341315	5/24 (21%)
		TM helix 7	313..338	CDD:341315	5/38 (13%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910