DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CapaR and srw-55

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_506993.2	Gene:	srw-55 / 188146	WormBaseID:	WBGene00005802	Length:	344	Species:	Caenorhabditis elegans

Alignment Length:	348	Identity:	71/348 - (20%)
Similarity:	130/348 - (37%)	Gaps:	88/348 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 FITGVVGNL--LVCIVIIRHSAMHTATNYYLFS-LAVSD----LLYLLFGLPTEVFLYWHQ---Y 133
            |...|:|..  |....::...|:.|.|.|:..: :|:.|    .|.::..||:  |.|.:|   .
Worm    23 FFIAVIGGFLNLFHFAVLTRPALRTFTIYFFMTIIAICDFFRLFLVIVTALPS--FYYTYQQSIL 85

  Fly   134 PDLFGMPFCKIR-------AFISEACTYVSVFTIVAFSMERFLAICHPL--HLYAMVGFKRAIRI 189
            |.....|:....       :.:|:....:.|:.:||.|:.|.:||..||  .:...:..|..||:
Worm    86 PSECIPPYSYFTVSMELGFSILSKISGKLVVWIVVAMSILRLIAIKCPLSPRVQKTIETKHGIRL 150

  Fly   190 ITALWIVSFISAIPFGLLSDIQY--------LNYPLDHSRIEESAFCS----------------M 230
            |..:    .|:.|||..| :|||        |..|.:..::.:...|.                :
Worm   151 IYFI----CITLIPFAYL-EIQYNNVRVFQTLTLPQNCEKVSKITKCKEYIIVPAKYDYYILSCI 210

  Fly   231 SPKIVNEIPVFEVSFCIFFVIPMILIILLYGRMGAKIRSRTNQKLGVQQGTNNRETRNSQMRKKT 295
            ...:...||.|..:|...::|..:          .|:|...:.:......:|.|.|
Worm   211 EGYLFRVIPSFMTTFATVWLIHQL----------KKMRRSASTRSSANSDSNERFT--------- 256

  Fly   296 VIRMLAAVVITFFVCWFPFHLQRLIFLYA-KNMDNYLD-------INEALFSIAGFAYYVSCTVN 352
              :::....:.|.:...|..: .|:|.|. :..|:.:.       |.:.|..:.|..:::||
Worm   257 --KLVVLFNVIFLLSTAPTEI-ILVFEYVYEGYDSLISIITKFQFICDILPLLNGLIHFLSC--- 315

  Fly   353 PIVYSVMSRRYRVAFRELL-CGK 374
                ..||..||.|..::: |.|
Worm   316 ----FFMSSHYRKAVTKMIGCRK 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	68/340 (20%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	62/321 (19%)
srw-55	NP_506993.2	TM helix 1	17..43	CDD:341315	4/19 (21%)
		7tm_GPCRs	21..333	CDD:391938	69/345 (20%)
		TM helix 2	50..75	CDD:341315	5/24 (21%)
		TM helix 3	94..131	CDD:341315	7/36 (19%)
		TM helix 4	143..172	CDD:341315	12/33 (36%)
		TM helix 5	204..229	CDD:341315	4/24 (17%)
		TM helix 6	256..280	CDD:341315	4/35 (11%)
		TM helix 7	294..319	CDD:341315	5/31 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910