DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and srw-26

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_001309436.1	Gene:	srw-26 / 188144	WormBaseID:	WBGene00005773	Length:	354	Species:	Caenorhabditis elegans

Alignment Length:	364	Identity:	72/364 - (19%)
Similarity:	148/364 - (40%)	Gaps:	81/364 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 ITGV-VGNLLVCIVIIRHSAMHTAT-NYYLFSLAVSDLLYL---LFGLPTEVFLYWHQYPDLFG- 138
            |||| |...:..:.::.:.:|...| |.:|..:|:|||:.:   :|...|:   ::..|...:|
Worm     8 ITGVGVFTNIFHLAVLNNKSMRKFTINIFLIGIAISDLIRMNCKMFHTATK---FYQLYQSHWGS 69

  Fly   139 ------------MPFCKIRAFISEACTYVSVFTIVAFSMERFLAICHPL--HLYAMVGFKRAIRI 189
                        :.||.....|..|  ::.::..|..::.|.|.:.:||  .:.::...|...||
Worm    70 CVPRSSYLLMAIINFCSPTGHIFGA--HLGIWFAVGMAVIRVLVVKYPLSSRMNSLTKSKYGSRI 132

  Fly   190 I-------TALWIVSF--ISAIPFGLLS-------DIQYLNYPLDHSRIEESAFCSMSPKIVNEI 238
            :       ...||..:  ::.||..|.|       |...:.|.|:.:.|.::       :.:.||
Worm   133 VFFIVLCMLPFWIFDYFQVTVIPATLPSNCANFSVDSYQVQYILEETHIFDN-------ERIYEI 190

  Fly   239 PVFEVSFCIFF----VIPMILIILLYGRMGAKIRSRTNQKLGVQQGTNNRETRNSQMRKKTVIRM 299
            .||.......|    ::|:..::|:.    .|.|:|.:.:|  .:..:|   :||..|..|::..
Worm   191 NVFVQGLLFEFTPSIILPIATLLLVV----EKRRARKSTEL--MKSVSN---QNSSDRSTTLVIF 246

  Fly   300 LAAVVITFFVCWFP--------FHLQRL------IFLYAKNMDNYLDINEALFSIAGFAYYVSCT 350
            :   .|||.:...|        |.:.::      :.|.:..:...::.|.|:..:..:..:...|
Worm   247 M---TITFVIATAPRGFSYVGKFIISQVGDDKPKLTLQSMIVGFIINFNSAIHFLLCYCLHNVFT 308

  Fly   351 VNPIVYSVMSRRYRVAFRELLCGKAVGAYYNSGFARDHS 389
            ::.....::.:|.|   ::|.|...:..|....|.|:.|
Worm   309 ISECGERIVQKRSR---KDLGCYSVLYKYEIKYFERNWS 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	63/341 (18%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	59/323 (18%)
srw-26	NP_001309436.1	7TM_GPCR_Srw	3..303	CDD:370978	63/318 (20%)
		TM helix 1	3..26	CDD:341315	5/17 (29%)
		TM helix 2	33..58	CDD:341315	7/24 (29%)
		TM helix 3	82..113	CDD:341315	7/32 (22%)
		TM helix 4	127..147	CDD:341315	5/19 (26%)
		TM helix 5	188..213	CDD:341315	6/24 (25%)
		TM helix 6	235..265	CDD:341315	8/32 (25%)
		TM helix 7	278..301	CDD:341315	3/22 (14%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910