DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and srw-20

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_507325.1	Gene:	srw-20 / 188136	WormBaseID:	WBGene00005767	Length:	345	Species:	Caenorhabditis elegans

Alignment Length:	369	Identity:	77/369 - (20%)
Similarity:	142/369 - (38%)	Gaps:	94/369 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 PKEFVAFVLGPQTLPLYKAVLI--TIIFGGIFITGVVGNLLVCIV-IIRHSAMHTAT------NY 105
            |.:.:|.::.    .|:..|||  .:...||||.    .|.:|:. |..:|...|..      :|
Worm    14 PLQIIALLVN----SLHLLVLIRKPLRCCGIFIF----MLAICLADITNYSLSFTGAARRYKHDY 70

  Fly   106 YLFSLAVSDLL--YLLFGLPTEVFLYWHQYPDLFGMPFCKIRAFISEACTYVSVFTIVAFSMERF 168
            .|..:.:.|.:  :|::|        |    .:..:|...:..|.|....| ||:..|..|..|.
Worm    71 MLTQMYIEDRMNPFLVYG--------W----IIVDVPGQLMALFYSITRKY-SVWLAVVMSAVRT 122

  Fly   169 LAICHPLH-LYAMVGFKR-AIRIITALWI-VSFISAIPFGLLSDIQYLNYPL-----------DH 219
            |::..|:| ....:..|. ::||..|::| |.|:......:...|::|...|           .|
Worm   123 LSVLFPMHNRIQKINEKTVSVRISIAVFIFVMFVDFTELAMTYRIKWLPSILFYNNSKSKPEWQH 187

  Fly   220 SRIEESAFCSMSPKIVNEIPVFEVSFCIFFV----IPMILIILLYGRMGAKIRSRTNQKLGVQQG 280
            ..:.:...|..|.:|       .:|.|..||    .|::..||:     .::|:...:|..:.:.
Worm   188 YVLVDCFSCVTSLQI-------HISICSRFVPSLIYPILTTILI-----LQLRTIKKRKANLLKS 240

  Fly   281 TNNRETRNSQMRKKTVIRMLAAVVITF--------FVCWFPFHLQRLIFLYAKNMDNYLDINEAL 337
            |::.::.|.       .:|:..:.|||        |..|...:          ||:.::|.::..
Worm   241 TSSNQSDNK-------FKMILWLTITFMLSEGLTGFTGWMQLY----------NMNIHIDTSQKF 288

  Fly   338 FSIAGFAYYVSCTVNPI-------VYSVMSRRYRVAFRELLCGK 374
            .......||...||..:       :.::||..||:..:.:.|.|
Worm   289 ARFWVSTYYAMFTVRAVNSLSHILICALMSTVYRMELKSIFCKK 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	66/330 (20%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	61/312 (20%)
srw-20	NP_507325.1	7tm_GPCRs	15..332	CDD:391938	75/366 (20%)
		TM helix 2	40..75	CDD:341315	10/38 (26%)
		TM helix 3	93..126	CDD:341315	10/33 (30%)
		TM helix 4	142..163	CDD:341315	6/20 (30%)
		TM helix 5	196..222	CDD:341315	8/32 (25%)
		TM helix 6	244..274	CDD:341315	7/36 (19%)
		TM helix 7	292..318	CDD:341315	4/25 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910