DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and srw-111

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_493064.1	Gene:	srw-111 / 187381	WormBaseID:	WBGene00005858	Length:	352	Species:	Caenorhabditis elegans

Alignment Length:	373	Identity:	87/373 - (23%)
Similarity:	161/373 - (43%)	Gaps:	83/373 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 EEDYACGTFNCSPKEFVAFVLGPQTLPLYKAVLITIIFGGIFITGVVGNLLVCIVIIRHSAMHTA 102
            |||.:.....|...:.::.|  ..||.::...|..:.        ::.|:|..|::.|.|..:|:
Worm    14 EEDNSTALVLCQLTDKISLV--SMTLYMFSPFLSVLC--------ILINILHLIILTRKSMRNTS 68

  Fly   103 TNYYLFSLAVSDLLYLLFGLPTEVFLYWHQYPD-LFGMPFCKIRAFI----------SEAC-TYV 155
            .|..:.:.||||:.|||. :.:.::|....|.| .||.|...:...:          |:.| |::
Worm    69 INVIMTAAAVSDICYLLI-VASRIYLLIGMYTDPCFGSPVSYLSVVLDIIIEILNDCSQRCSTWI 132

  Fly   156 SVFTIVAFSMERFLAICHPLHLYAMVGFKRAIRIITALWIVSF--ISAIPFGLLSDIQYLNYPLD 218
            |    ::.:..|.|.:.:|:.    ..|:|..:..|||:::..  ||::||.|...|..
Worm   133 S----LSIATIRTLVVRNPMD----PKFERLTKPYTALFVILGVPISSLPFSLAFQIGI------ 183

  Fly   219 HSRI-EESAFCSMSPK-----IVNE-IPVFE----VSFCIFFVIPMILIILLYGRMGAKIRSRTN 272
              || ::..|....||     ||:: :.|.:    ||..|..:||.:|..:..|.:..::...|.
Worm   184 --RITKQKEFSECYPKGVLTYIVDQKVSVKQLSSTVSAIISNIIPCLLFPIFAGLLVKEMHKATE 246

  Fly   273 QKLGVQQGTNNRETRNSQMRKKTV-----IRMLAAVVITFFVCWFPFHLQRLIFLYAKN---MDN 329
                     |.|...:|   |||:     .|::....:.||:..||..:.|.:.|.:..   ...
Worm   247 ---------NQRRLTSS---KKTIDYNKTTRLVFYNTLFFFISLFPLGVSRTLLLLSSTEFLWPM 299

  Fly   330 YLDINE---ALFSIAGFAYYVSCTVNPIVYSVMSRRYRVAFREL-LCG 373
            ::|:..   .:|::...:::|       :|.:||.:|:...:|| |||
Worm   300 FIDLESIVLVIFTLNTMSHFV-------IYMLMSSQYQNTTKELFLCG 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	79/326 (24%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	70/306 (23%)
srw-111	NP_493064.1	7TM_GPCR_Srw	60..340	CDD:370978	74/315 (23%)
		TM helix 2	69..97	CDD:341315	9/28 (32%)
		TM helix 3	115..145	CDD:341315	6/33 (18%)
		TM helix 4	155..175	CDD:341315	5/19 (26%)
		TM helix 5	211..236	CDD:341315	6/24 (25%)
		TM helix 6	258..288	CDD:341315	6/29 (21%)
		TM helix 7	301..326	CDD:341315	4/31 (13%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910