DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CapaR and srw-119

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_503818.1	Gene:	srw-119 / 187328	WormBaseID:	WBGene00005866	Length:	367	Species:	Caenorhabditis elegans

Alignment Length:	334	Identity:	78/334 - (23%)
Similarity:	145/334 - (43%)	Gaps:	67/334 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 IFITGVVGNLLVCIVIIRHSAMHTATNYYLFSLAVSDLL------YLLFGLPTEVFLYWHQYPD- 135
            |.|:.|:.||:...::.|.....::.|..:.::|:.|:|      .|:|...:::|  :..||.
Worm    45 ISISSVLINLIHFFILTRKPMRTSSINILMAAVALYDILTSLKQIELIFEQNSDIF--FDCYPTY 107

  Fly   136 LFGMPFCKIRAFI----SEACTYVSVFTIVAFSMERFLAICHPLH-LYAMVGFKRAIRIITALWI 195
            .||:...:|...|    |..|   |.:.||:.:..|.:.:.:||: .|..:|..:|..::    |
Worm   108 TFGVGLRRIILDIAKDYSRRC---STWFIVSIAFIRTVMVRNPLNSTYQSLGKPKASVVV----I 165

  Fly   196 VSFISA-IPFGLLS--DIQYLN-------------YPLDHSRI--EESAFCSMSPKIVNEIPVFE 242
            |...:| :|..:..  :.|::.             |.:..|::  ....|.:....:.|.. |.:
Worm   166 VGVCAASLPISVFKYFENQFVEKEPLYDCAQNGTYYYVTMSKLFTANDGFLAKYFSLFNSF-VSD 229

  Fly   243 VSFCIFF-VIPMILIILLY--GRMGAKIRSRTNQKLGVQQGTNNRETRNSQMRKKTVIRMLAAVV 304
            :..|:.. ::.::||:.|:  .:..|.|.|.||.|       ||..|      .||  .::..|.
Worm   230 IIPCLLLPIVTLLLIMNLWKTAKKRANITSATNHK-------NNNST------SKT--GLVFCVT 279

  Fly   305 ITFFVCWFPFHLQRLIFLYAKNMDNYLDINEALFSIAGFAYYVSCTVNP----IVYSVMSRRYRV 365
            ||||:..||:.|. |.||:..:.|:.:   ..:.|..||.:.:..|:|.    .|..::|.:||.
Worm   280 ITFFIVEFPYGLS-LGFLWMFDYDSGI---SRILSFFGFIFSMLITLNTCTHLFVCLIISSQYRK 340

  Fly   366 A-FRELLCG 373
            : .....||
Worm   341 STIHAFTCG 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	75/327 (23%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	69/307 (22%)
srw-119	NP_503818.1	7TM_GPCR_Srw	53..349	CDD:370978	73/324 (23%)
		TM helix 2	71..93	CDD:320109	5/21 (24%)
		TM helix 3	114..138	CDD:320109	7/26 (27%)
		TM helix 4	163..179	CDD:320109	4/19 (21%)
		TM helix 5	218..241	CDD:320109	3/23 (13%)
		TM helix 6	269..295	CDD:320109	12/34 (35%)
		TM helix 7	310..335	CDD:320109	6/24 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910