DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and srw-120

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_503816.2	Gene:	srw-120 / 187326	WormBaseID:	WBGene00005867	Length:	370	Species:	Caenorhabditis elegans

Alignment Length:	329	Identity:	77/329 - (23%)
Similarity:	137/329 - (41%)	Gaps:	78/329 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 IFITGVVGNLLVCIVIIRHSAMHTATNYYLFSLAVSDLL------YLLFGLPTEVFLYWHQYPD- 135
            |.|:.|:.||:...::.|.....::.|..:.::|:.|:|      .|:|...:::|  :..||.
Worm    45 ISISSVLINLIHFFILTRKPMRTSSINILMAAVALYDILTSLKQIELIFEQNSDIF--FDCYPTY 107

  Fly   136 LFGMPFCKIRAFI----SEACTYVSVFTIVAFSMERFLAICHPLH-LYAMVGFKRAIRIITALWI 195
            .||:...:|...|    |..|   |.:.||:.:..|.:.:.:||: .|..:|..:|..::    |
Worm   108 TFGVGLRRIILDIAKDYSRRC---STWFIVSIAFIRTVMVRNPLNSTYQSLGKPKASVVV----I 165

  Fly   196 VSFISAIPFGLLSDIQYLNYPLDHSRIEESAFCSMSP----------KIVNEIPVFEVS------ 244
            |...:|            :.|:...:..|:.|....|          .||....:|..:
Worm   166 VGVCAA------------SLPISVFKYFENQFVEKEPLYDCAQNGTYYIVTMSDLFMKNNGFLAK 218

  Fly   245 -FCIF--FV---IPMILI----ILLYGRMGAKIRSRTNQKLGVQQGTNNRETRNSQMRKKTVIRM 299
             |.:|  ||   ||.:|:    :||...:....:.|.|    :...:.|    |:.|.|..::
Worm   219 YFSLFNSFVSDIIPCLLLPIVTLLLIMNLWKTAKKRAN----ITSVSKN----NNSMSKTGLV-- 273

  Fly   300 LAAVVITFFVCWFPFHLQRLIFLYAKNMDNYLDINEALFSIAGFAYYVSCTVNP----IVYSVMS 360
             ..|.||||:..||:.|. |.||:..:.|:.:   ..:.|..||.:.|..|:|.    .|..::|
Worm   274 -FCVTITFFIVEFPYGLS-LGFLWMFDYDSGI---SRILSYFGFIFSVLITLNTCTHLFVCLIIS 333

  Fly   361 RRYR 364
            .:||
Worm   334 SQYR 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	74/322 (23%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	70/312 (22%)
srw-120	NP_503816.2	7TM_GPCR_Srw	53..347	CDD:370978	74/321 (23%)
		TM helix 2	71..93	CDD:320109	5/21 (24%)
		TM helix 3	114..138	CDD:320109	7/26 (27%)
		TM helix 4	163..179	CDD:320109	4/31 (13%)
		TM helix 5	218..241	CDD:320109	7/22 (32%)
		TM helix 6	270..293	CDD:320109	9/26 (35%)
		TM helix 7	308..333	CDD:320109	7/24 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910