DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and srw-121

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_503814.2	Gene:	srw-121 / 187324	WormBaseID:	WBGene00005868	Length:	362	Species:	Caenorhabditis elegans

Alignment Length:	339	Identity:	72/339 - (21%)
Similarity:	137/339 - (40%)	Gaps:	68/339 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 IFITGVVGNLLVCIVIIRHSAMHTATNYYLFSLAVSDLL--------------YLLFG-LPTEVF 127
            |.|:.|:.|||...::.|.....::.|..:.::|:.|:.              |:.|. ||
Worm    45 ISISSVIINLLHFFILTRKPMRTSSINNLMAAVALFDIFTCFQQIEIIFEKYKYIFFSCLP---- 105

  Fly   128 LYWHQYPDLFGMPFCK-IRAFISEACTYVSVFTIVAFSMERFLAICHPL-HLYAMVGFKRAIRII 190
                  .|.:|:...: :...:.:.....|.:.|:..:|.|.|.:.:|| :.:..:|..:|..|:
Worm   106 ------KDTYGLVLARTLLIVVQDYARKCSTWLIIFIAMIRTLLVRNPLSNQFESLGKPKAAAIV 164

  Fly   191 TALWIVSFISAIPFGLLSDI--------------QYLNYPLDHSRIEESAFCSMSPKIVNEIPVF 241
            .|:..:|.:....|..|.:.              .|..|......::.....:....::|.: |.
Worm   165 IAIVCISSLPVSMFRFLENTLMESIPRQSCAPNRTYYEYVGSELFMDNEGSIAKYFNLLNSL-VS 228

  Fly   242 EVSFCIFFVIPMILIILLYGRMGAKIRSRTNQKLGVQQGTNNRETRNSQMRKKTVIRMLAAVVIT 306
            ::..||  .:|::..:|:|    |.::|...:...:...|      :...|.||  .::..|.|.
Worm   229 DIIPCI--SLPIVTCLLVY----AVLKSNKKRAKLISSYT------DKSSRGKT--GLVFCVAIM 279

  Fly   307 FFVCWFPFHLQ---RLIFLYAKNMDNYLDINEALFSIAGFAYYVSCTVNPIVYSVMSRRYR-VAF 367
            ||:..||:.|.   ..|||.|..:.|.|:...::||:  .....||| :.|:..:||.:|| ...
Worm   280 FFIVEFPYGLSIGTAWIFLLAPGVYNILNQLASIFSM--LITLNSCT-HLIICLIMSSQYRSTTI 341

  Fly   368 RELLCGKAVGAYYN 381
            :...||     |:|
Worm   342 QIFTCG-----YFN 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	66/323 (20%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	61/304 (20%)
srw-121	NP_503814.2	7TM_GPCR_Srw	41..347	CDD:370978	68/329 (21%)
		TM helix 2	71..93	CDD:320109	3/21 (14%)
		TM helix 3	116..138	CDD:320109	2/21 (10%)
		TM helix 4	163..179	CDD:320109	3/15 (20%)
		TM helix 5	218..241	CDD:320109	5/25 (20%)
		TM helix 6	270..292	CDD:320109	8/23 (35%)
		TM helix 7	308..333	CDD:320109	6/27 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910