DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and srw-91

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_503480.3	Gene:	srw-91 / 186991	WormBaseID:	WBGene00005838	Length:	367	Species:	Caenorhabditis elegans

Alignment Length:	360	Identity:	66/360 - (18%)
Similarity:	127/360 - (35%)	Gaps:	118/360 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 IFGGIFITGVVGNLLVCIVIIRHSAMHTATNYYLFSLAVSDLLYLLFGL---------------P 123
            |||||.      .:...:|:.|.:...|:....:.|:|:.|.|.::..:               |
Worm    43 IFGGIL------TIFHFLVLTRKAMKSTSIISLMISVAICDFLSMIVSISSKDMILNFYGSDCTP 101

  Fly   124 TEVFL----YWHQYPDLFGMPFCKIRAFISEACTYVSV-FTIVAFSMERFLA-ICHPLHLYAMVG 182
            ...||    :|         ....||..:....|:::| ..::.|.:.::.: :.:......:.|
Worm   102 PNSFLTFQIFW---------VLMSIRDGVVRCSTWLTVLMALIRFLVSKYASEVRYQKMSMFIFG 157

  Fly   183 FKRAIRIITALWIVSFISAIPFGLLSDIQYL-----------------NYPLDHSRIEESAFCSM 230
            ||.:...:       |||:    |:|...||                 |.|||      |.|...
Worm   158 FKSSAFSV-------FISS----LMSSCFYLCIKFVEIGTWTPANCCTNIPLD------SQFPLY 205

  Fly   231 SPKIVN--------EIPVFEVSFCIFF-VIPMILIILLYGRMGAKIRSRTNQKL--GVQQGTNNR 284
            ..::.:        .:.:|:....||. :||.|::.||...:..:::.....::  .|....|..
Worm   206 EQRVSDLFSLYDGAPVQIFQFINGIFSKLIPCIILPLLTTLLVVELKRTEKSRISSSVLYKNNTE 270

  Fly   285 ETRNSQMRKKTVIRMLAAVVITFFVCWFPFHLQRLIFLYAKNMDNYLDINEALFSIAGFAY-YV- 347
            :|.|            ..:::||           .||| |........:.:.::|..||.: |:
Worm   271 KTTN------------LVIIMTF-----------SIFL-ASLPTGIATVFQVIYSDLGFLFIYIN 311

  Fly   348 -----------SCTVNPIVYSVMSRRYRVAFRELL 371
                       :.:.|..:..:||.:||...::||
Worm   312 VDAICDTLLLWNASTNCFICFLMSSQYRNTAKKLL 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	61/349 (17%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	55/332 (17%)
srw-91	NP_503480.3	7TM_GPCR_Srw	36..349	CDD:370978	66/360 (18%)
		TM helix 2	66..93	CDD:341315	4/26 (15%)
		TM helix 3	111..141	CDD:341315	6/38 (16%)
		TM helix 4	159..180	CDD:341315	8/31 (26%)
		TM helix 5	221..246	CDD:341315	8/24 (33%)
		TM helix 6	271..297	CDD:341315	8/49 (16%)
		TM helix 7	310..335	CDD:341315	1/24 (4%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910