DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and srw-31

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_507435.2	Gene:	srw-31 / 186943	WormBaseID:	WBGene00005778	Length:	367	Species:	Caenorhabditis elegans

Alignment Length:	417	Identity:	78/417 - (18%)
Similarity:	147/417 - (35%)	Gaps:	133/417 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 FGEED--------YACGTFNCSPKEFVAFVLGPQTLPLYKAVLITIIFGGIFITGVVGNLLVCIV 92
            ||.|.        |..||||.. .:.|.||          |:::..:.|.|.:|          :
Worm    12 FGIESIRVFCAIAYFMGTFNYY-SDHVHFV----------ALIVGTVLGVIHLT----------I 55

  Fly    93 IIRHSAMHTATNYYLFSLAVSDL-----LYLLFGLPTEVFLYWHQYPDLFGMPFCKIRAFISEA- 151
            :.|......:.|.:|..:|.:::     :.::|                  :||..:|....|.
Worm    56 LTRKCMRALSINVFLIGIAAAEIFRAICILIIF------------------IPFFDLRYLSDEVS 102

  Fly   152 -CT----------------------YVSVFTIVAFSMERFLAICHPLH------LYAMVGFKRAI 187
             |:                      .|||:..||.::.|.|.:.:|::      ..|..|| |.:
Worm   103 DCSDPNSTVAVLSYNISASFMRLAEKVSVWFAVAIAVIRTLVMRYPVNGRINCLTQAKYGF-RIV 166

  Fly   188 RIITALWIVSFISAIPFGLLSDIQY--------------LNYPLDHSRIEESAFCSMSPKIVNEI 238
            .:||.|       .||||..|..:.              :.:..:.::|:   |.|.|.::....
Worm   167 VLITLL-------IIPFGAPSYFKLNSTSVRGWTPFTNCVTFSENSTKIK---FDSHSTELFGST 221

  Fly   239 PVFEVSFCI---------FFVIPMILIILLYGRMGAKIRSRTNQKLGVQQGTNNRETRNSQMRKK 294
            .|::::..|         ..::|:..|.|:.....|:              .|:..|::|.....
Worm   222 DVYKIALLIEGIFLEFTPSIILPITTISLIMDLRKAR--------------KNSLSTKSSASSSD 272

  Fly   295 TV--IRMLAAVVITFFVCWFPFHLQRLIFLYAKNMDNYLDINEALFSIAGFAYYVSCTVNPIVYS 357
            .|  |:::|.|.|||.....|.....::.::...|...:.|......:..|...:|...:.::..
Worm   273 AVRSIKLVAFVTITFLFTTTPLGFMYIVGIFIVKMPGVIMIVTKFARVLTFLTTLSGIAHILICY 337

  Fly   358 VMSRRYRVAFRELLCGKAVGAYYNSGF 384
            :||.:||....|:. ||....:.::.|
Worm   338 LMSTQYRSTAHEMF-GKKEKIFKSTSF 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	60/348 (17%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	55/330 (17%)
srw-31	NP_507435.2	7TM_GPCR_Srw	36..354	CDD:370978	68/381 (18%)
		TM helix 2	66..91	CDD:341315	4/42 (10%)
		TM helix 3	116..146	CDD:341315	7/29 (24%)
		TM helix 4	160..180	CDD:341315	10/27 (37%)
		TM helix 5	224..249	CDD:341315	2/24 (8%)
		TM helix 6	276..302	CDD:341315	7/25 (28%)
		TM helix 7	315..340	CDD:341315	2/24 (8%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910