DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CapaR and srw-143

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_503798.3	Gene:	srw-143 / 186788	WormBaseID:	WBGene00005890	Length:	368	Species:	Caenorhabditis elegans

Alignment Length:	382	Identity:	71/382 - (18%)
Similarity:	146/382 - (38%)	Gaps:	106/382 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 DYACGTFNCSPKEFVAFVLGPQTLPLYKAVLITIIFGGIF-------ITGVVGNLLVCIVIIRHS 97
            |.|...|.|   :|.|        .|:|      |.|.:|       |..:..|:...:::||..
Worm    15 DNATAIFLC---QFEA--------RLFK------ISGHVFNYEHYLSIASIFINIFHFLILIRKP 62

  Fly    98 AMHTATNYYLFSLAVSDLLYLLFGL-----PTEVFLY-------WHQYPDLFGMPFCKIRAFISE 150
            ...::.|..:..:::.|:..:||.:     |:..:::       |:     |.:...||...:.:
Worm    63 LRSSSINIIMAFISIFDICSMLFRMKQSYGPSIEYIFDPCMQSKWY-----FNVYLEKILLVVKD 122

  Fly   151 ACTYVSVFTIVAFSMERFLAICHPLHLYAMVGFKRAIRIITALWIVSFISAIPFGLL-------S 208
            .....|.:.:.:.::.|.|.|.:|::    ..::|.....|:|:.:..|:.| ||.:       |
Worm   123 HSQRSSTWLLFSIALIRTLVIRNPMN----PKYERLAHPPTSLFTMICINLI-FGPISIATFFGS 182

  Fly   209 DIQYLN------------YPLDHSRIEE-------SAFCSMSPKIVNEIPVFEVSFCIFFVIPMI 254
            ||...|            |.||.|...:       ..:..::..:...||.|     ||.::.:.
Worm   183 DITSQNHTSSCDPDGVLFYYLDISASYKQNDGMILKIYTLINSVVSTIIPCF-----IFPIVTVF 242

  Fly   255 LIILLYGRMGAKIRSRTNQKLGVQQGTNNRETRNSQMRKKTVIRMLAAVVITFFVCWFPFHLQ-R 318
            |:..|:       ::..|:|........|..::|:|:     :..|..|   ||:..||..:. .
Worm   243 LVKELW-------KAEANRKRLFSSKKVNDSSKNTQL-----VLFLTCV---FFIAQFPIGISIG 292

  Fly   319 LIFLYAKNMDNYLDINEA--LFSIA----GFAYYVSCTVNPIVYSVMSRRYRVAFRE 369
            ..:.:::.....:.::|.  :||:.    .|:::..|.       .||.:||...::
Worm   293 ASYFFSETPGFMIILHEISYIFSVILVANTFSHFFICI-------FMSSQYRAELKK 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	59/330 (18%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	55/315 (17%)
srw-143	NP_503798.3	7TM_GPCR_Srw	38..347	CDD:370978	60/342 (18%)
		TM helix 2	69..94	CDD:320109	4/24 (17%)
		TM helix 3	115..137	CDD:320109	3/21 (14%)
		TM helix 4	162..178	CDD:320109	4/16 (25%)
		TM helix 5	218..241	CDD:320109	5/27 (19%)
		TM helix 6	267..292	CDD:320109	8/32 (25%)
		TM helix 7	307..333	CDD:320109	5/32 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910