DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and srw-59

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_506996.1	Gene:	srw-59 / 186771	WormBaseID:	WBGene00005806	Length:	349	Species:	Caenorhabditis elegans

Alignment Length:	347	Identity:	74/347 - (21%)
Similarity:	133/347 - (38%)	Gaps:	100/347 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 IFITGVVGNLLVCIVIIRHSAMHTATNYYLFSLAVSD----LLYLLFGLPTEVFLYWHQYPDLFG 138
            |.:.||..|:...||:.|.|......|.:|..:|:.|    |.|:|..||.    |.::|.
Worm    36 IAVIGVFVNIFHLIVLTRKSLRVYTINIFLIGIAICDFIRLLSYVLLALPD----YHYRYQ---- 92

  Fly   139 MPFCKIRAFISEAC----TYVSVFTI------------------VAFSMERFLAICHPLHLYAMV 181
                  ::.:|..|    :|.|.|..                  ||.::.|.:.:.:.|.|.|
Worm    93 ------KSIMSSICIPPPSYASCFLFVHFTPIPRVFQDLAVWFGVAMAVLRVIILKYSLSLKA-- 149

  Fly   182 GFKRAIRIITALWIVSFISAIPFGLLSDIQYLNYPLDHSRIEE----------SAFCSMSPKIV- 235
              :..|...:.:||: |:..:|     .|.|..:....:.|.|          :.|...||:|:
Worm   150 --QNLISSNSGIWIL-FVVCLP-----HIVYWIFEFQWTEIREYGIWEIPSGCANFTYTSPRIIY 206

  Fly   236 --------NEIPVFEVSFCIFF------VIPMILIILLYGRMGAKIRSRTNQKLGVQQGTNNRET 286
                    ||..:....  |||      ::|::.|:|:|.....|..:.:|        .||...
Worm   207 SMGPEEYQNETLLLVEG--IFFTLIPSIILPIVTIVLIYFLKTMKRSTASN--------NNNHNA 261

  Fly   287 RNSQMRKKTVIRMLAAVVITFFVCWFPFHLQRLIFLYAKNMDNYLDIN---EALFSIAGFAYYVS 348
            |::        :|:|.|.:||.:...|.   .:.:|| ::.|....|:   .....|..|...::
Worm   262 RST--------KMVALVTVTFLLATVPL---GITYLY-QHTDFSFGISFFCSMFVIICEFVSLIN 314

  Fly   349 CTVNPIVYSVMSRRYRVAFREL 370
            .|::.::...:|.:|:...||:
Worm   315 GTMHFLLCVCISSQYQRIVREM 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	71/340 (21%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	67/324 (21%)
srw-59	NP_506996.1	7TM_GPCR_Srw	31..340	CDD:370978	74/347 (21%)
		TM helix 1	34..53	CDD:320109	6/16 (38%)
		TM helix 2	62..84	CDD:320109	7/21 (33%)
		TM helix 3	113..135	CDD:320109	2/21 (10%)
		TM helix 4	160..176	CDD:320109	6/21 (29%)
		TM helix 5	216..239	CDD:320109	5/24 (21%)
		TM helix 6	261..286	CDD:320109	7/35 (20%)
		TM helix 7	301..326	CDD:320109	3/24 (13%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910