DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and srw-51

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_507344.1	Gene:	srw-51 / 185526	WormBaseID:	WBGene00005798	Length:	352	Species:	Caenorhabditis elegans

Alignment Length:	357	Identity:	69/357 - (19%)
Similarity:	138/357 - (38%)	Gaps:	94/357 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 IFITGVVG---NLLVCIVIIRHSAMHTATNYYLFSLAVSDLLYLLFGLPTEVFLYWHQYPDLFGM 139
            ||:..::|   |:...:|:.|.|......|.::..:|:.|...::..:......::..|......
Worm    25 IFVVSIIGIILNVFHFLVLFRKSMRQLTINIFMIGIAICDFSQMISFVVVMTSQFYINYKTTQIS 89

  Fly   140 PFC------------KIRAFISEACTYVSVFTIVAFSMERFLAICHPL------HLYAMVGFKRA 186
            |.|            .|..|||.....::|:..|:.::.|...|.||.      ::|:    |..
Worm    90 PECYPPQSYIEYKINHIFTFISNVSPKLAVWLGVSLAILRASVIRHPTNSSIQNYIYS----KHG 150

  Fly   187 IRIITALWIVSFISAIPFGLLSDIQYL-----------------------NYPLDHSRIEESAFC 228
            |||:..:       .:|:.......|.                       .|.|.::..:||:|
Worm   151 IRILLTI-------CLPYACYFIYDYTAHSTTISETWELPPECANTSEPDTYTLYYTEYDESSF- 207

  Fly   229 SMSPKIVNEIPVFEVSFCIFFVIPMIL-----IILLYGRMGAKIRSRTNQKLGVQQGTNNRETRN 288
                    .|.:| :...:|.:||.||     |:|||       ..:..:|:     ..:|..:|
Worm   208 --------RISLF-IDGILFKLIPSILLPLFTIVLLY-------EMKKTRKV-----ATSRSFQN 251

  Fly   289 SQMRKKTVIRMLAAVVITFFVCWFP---FHLQRLIFLYAKNMDNYLDINEALFSIAGFAYYVSCT 350
            |..:.::. :::..|.|||.:...|   .::.:.|||.:..:.|:.:..:::|.:...   ::.|
Worm   252 SNSKDRST-KLVTFVTITFLLSTVPLGILYIIKSIFLQSLVISNFANKLQSIFVLISI---INGT 312

  Fly   351 VNPIVYSVMSRRYRVAFRELLCGKAVGAYYNS 382
            ::.::...||.:||...:     .|||..:.|
Worm   313 LHFLICFFMSSQYRNTVK-----NAVGWKFKS 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	63/340 (19%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	59/322 (18%)
srw-51	NP_507344.1	7TM_GPCR_Srw	23..336	CDD:370978	68/352 (19%)
		TM helix 1	23..45	CDD:320109	5/19 (26%)
		TM helix 2	54..76	CDD:320109	3/21 (14%)
		TM helix 3	105..127	CDD:320109	6/21 (29%)
		TM helix 4	152..168	CDD:320109	3/22 (14%)
		TM helix 5	208..231	CDD:320109	7/23 (30%)
		TM helix 6	256..281	CDD:320109	5/25 (20%)
		TM helix 7	297..322	CDD:320109	2/27 (7%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910