DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and srw-44

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_507223.1	Gene:	srw-44 / 184480	WormBaseID:	WBGene00005791	Length:	385	Species:	Caenorhabditis elegans

Alignment Length:	360	Identity:	65/360 - (18%)
Similarity:	130/360 - (36%)	Gaps:	98/360 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 ITIIFGGIFITGVVGNLLVCIVIIRHSAMHTATNYYLFSLAVSDLLYLLFGLPTEVFLYWHQYPD 135
            :.|.|.|.|     ||:....|:.|.|....:.:.:|.|:|:.|.:.::..:.|...:::.:|..
Worm    46 LVIAFVGFF-----GNIFHLAVLTRKSMRILSVSTFLISIAICDFVRMMSTIVTLSPIFYREYLS 105

  Fly   136 LFGMPFCKIRAFISEACTYVSVFTIVAFSMERFLAICHPLHLYAMVGFKRAIRIITALWIVSFIS 200
            |      .:|.......:|:.::.|..|         |.|...:|         ..::|...|::
Worm   106 L------HVRLKCQPPPSYLEMYIIYVF---------HSLETVSM---------NLSVWFAVFMT 146

  Fly   201 AIPFGLLSDIQYLNYPLDHSRIE-----ESAFCSMSPKIVNEIPVFEVSFCIFFVIP-------- 252
            .  |..|:    :.||| :.||:     ||..|::....:..:|...:||.:..:.|
Worm   147 I--FRALA----IRYPL-NKRIKSLITSESGLCTVITITILILPFCCLSFFLRTLFPASTWYPSP 204

  Fly   253 --------------MILIILLYGRMGAKIRSRTNQKL----------------------GVQQGT 281
                          .:|...|.|.:|.: .|...||:                      .:::..
Worm   205 GCKKFSKGYTQIQYRLLATELSGELGTE-TSEIMQKVEGLLFKFLPSVVLSLATFALVFAIRKHK 268

  Fly   282 NNRETRNSQMRKKTVIRMLAAVVITFFVCWFPFHLQRLIFLY------AKNMDNYLDINEALFSI 340
            ....|..::..|:...::::.|..||.:...|   |.::|:.      ...|...:|   .|.:.
Worm   269 KKNCTPGNKSDKEKTTKLVSFVTFTFLIAIVP---QGILFMIMFKVFETSMMGAVID---ELSTA 327

  Fly   341 AGFAYYVSCTVNPIVYSVMSRRYRVAFRELLCGKA 375
            ..|...::.|::.::...|...||...|.:.|.|:
Worm   328 LSFLSVINGTIHLLIIYFMCSEYRKTIRCMFCRKS 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	60/343 (17%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	55/325 (17%)
srw-44	NP_507223.1	TM helix 1	41..65	CDD:320109	7/23 (30%)
		7TM_GPCR_Srw	44..361	CDD:370978	64/357 (18%)
		TM helix 2	74..96	CDD:320109	5/21 (24%)
		TM helix 3	125..147	CDD:320109	6/39 (15%)
		TM helix 4	172..188	CDD:320109	2/15 (13%)
		TM helix 5	235..258	CDD:320109	2/22 (9%)
		TM helix 6	282..306	CDD:320109	5/26 (19%)
		TM helix 7	322..347	CDD:320109	4/27 (15%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910