DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and srw-139

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_503813.2	Gene:	srw-139 / 183445	WormBaseID:	WBGene00005886	Length:	376	Species:	Caenorhabditis elegans

Alignment Length:	330	Identity:	63/330 - (19%)
Similarity:	127/330 - (38%)	Gaps:	76/330 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 NLLVCIVIIRHSAMHTATNYYLFSLAVSDLLYLLFGLP---TEVFLYWHQYPD-------LFGMP 140
            |::..|::.|.|...::.|..:.::|..|:..||..:.   .::.:|::....       ||...
Worm    54 NIIHLIILTRKSLRSSSVNLIMAAVAFFDICTLLIEIEQIIQDLIIYFNNCYQATSYAWILFNTS 118

  Fly   141 FCKIRAFISEACTYVSVFTIVAFSMERFLAICHPLHLYAMVGFKRAIRIITALWIVS--FISAIP 203
            ...:|.: |..|   |.:..::.::.|.|.|.:||    :..:.:..:.|.||:::|  .:.:||
Worm   119 VESLRDY-SRRC---STWLCLSIALLRLLVISNPL----VPKYIKLTKPIGALYVISVVLLGSIP 175

  Fly   204 FGLLSDIQY-LNYPLDHSRIEESA----FCSMSPK------------------IVNEIPVFEVSF 245
            ..:...::: :|..:..|:...:.    |...|..                  :.|.||.|....
Worm   176 ISVFDFMKFKINGIIRPSQCHPNGTLVYFIKFSDAFMENNQALLKIATTTNAIVTNIIPCFLYPI 240

  Fly   246 CIFFVIPMILIILLYGRMGAKIRSRTNQKLGVQQGTNNRETRNSQMRKKTVIR---MLAAVVITF 307
            ..||::..:|::                       ..||.:.:|.......:|   ::.|....|
Worm   241 FTFFLVTQLLLV-----------------------NKNRRSISSSKSSAESLRTTHLVLAFTAMF 282

  Fly   308 FVCWFPFHLQ---RLIFLYAKNMDNYLDINEALFSIAGFAYYVSCTVNPIVYSVMSRRYRV-AFR 368
            ||..||..:.   ..:|.....:...|...|.:|::..:|.:.|   :.|:.|:||.:||. |..
Worm   283 FVAEFPLGVSSSLAYLFFDVPGIVIILRYCEMIFTVILYANFSS---HFIICSLMSSQYRSNAMS 344

  Fly   369 ELLCG 373
            ...||
Worm   345 LATCG 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	63/330 (19%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	55/310 (18%)
srw-139	NP_503813.2	7TM_GPCR_Srw	42..349	CDD:370978	61/328 (19%)
		TM helix 2	72..94	CDD:320109	5/21 (24%)
		TM helix 3	117..139	CDD:320109	4/25 (16%)
		TM helix 4	164..180	CDD:320109	3/15 (20%)
		TM helix 5	220..243	CDD:320109	4/22 (18%)
		TM helix 6	270..294	CDD:320109	7/23 (30%)
		TM helix 7	310..335	CDD:320109	6/27 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910