DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and srw-117

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_503812.1	Gene:	srw-117 / 183444	WormBaseID:	WBGene00005864	Length:	372	Species:	Caenorhabditis elegans

Alignment Length:	375	Identity:	73/375 - (19%)
Similarity:	157/375 - (41%)	Gaps:	88/375 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 IFITGVVGNLLVCIVIIRHSAMHTATNYYLFSLAVSDL------LYLLFGLPTEVFLYWHQYP-D 135
            |.::.::.|::...::.|.....::.|..:.::|:.|:      :.::|...|.:|  :..:| |
Worm    45 ISVSSILINIVHVFILTRKPMRTSSINILMAAVALFDIFTNFQQIEIIFERNTSIF--FECFPTD 107

  Fly   136 LFGMPFCK-IRAFISEACTYVSVFTIVAFSMERFLAICHPLH-LYAMVGFKRAIRII-------- 190
            .:|:...: |...:::.....|.:.||:.:..|.|.:.:||| .|..:|...|..|:
Worm   108 TYGVILTRAIFDIVNDYSRRCSTWFIVSIAFMRTLMVRNPLHSTYQSLGNPNASVIVISGVCAAS 172

  Fly   191 ----------TALWIVS---FISAIPFGLLSDIQYLNYPLDHSRIEESAFCSMSPKIVNEIPVFE 242
                      |..::|:   ::.|     |....|| ..:.|..::.:.|.:....:.|.. |.:
Worm   173 LPISIFKFFETQFFVVTESLYVCA-----LQGTYYL-AAMSHFFMKNNGFIAKYFSLFNSF-VSD 230

  Fly   243 VSFCIFFVIPMILIILLY-----GRMGAKIRSRTNQKLGVQQGTNNRETRNSQMRKKTVIRMLAA 302
            :..|:  ::|::.::|:.     .:..|.|.|.:|:        ||       .|.||  .::..
Worm   231 IIPCL--LLPIVTVLLVMDLWKTAKKRANIVSVSNK--------NN-------FRSKT--GLVFC 276

  Fly   303 VVITFFVCWFPFHLQ-RLIFLYAKNMDNYLDINEALFSIAGFAYYVSCTVNP----IVYSVMSRR 362
            |.|.||:..||:... ..:::| ||....    :.:.:..||.:.:..|:|.    .:..::|.:
Worm   277 VTIMFFLVEFPYGSSLGAVWMY-KNAPGM----QQILAHVGFIFSMLITLNTCTHFFICLLISSQ 336

  Fly   363 YRVAFRELL-CGKAVGAYYNSGFARDHSSFRESSAYDRVHSVHVRASQHP 411
            ||.....:| ||     :.||         :::||...|.::.|::...|
Worm   337 YRKTIIHVLSCG-----FINS---------KKTSASKAVVNLPVQSKTLP 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	64/329 (19%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	59/310 (19%)
srw-117	NP_503812.1	7TM_GPCR_Srw	53..348	CDD:370978	63/327 (19%)
		TM helix 2	71..93	CDD:320109	3/21 (14%)
		TM helix 3	114..138	CDD:320109	4/23 (17%)
		TM helix 4	163..179	CDD:320109	1/15 (7%)
		TM helix 5	219..242	CDD:320109	4/25 (16%)
		TM helix 6	271..294	CDD:320109	7/24 (29%)
		TM helix 7	309..334	CDD:320109	4/24 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910