DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and srw-124

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_503810.2	Gene:	srw-124 / 183440	WormBaseID:	WBGene00005871	Length:	368	Species:	Caenorhabditis elegans

Alignment Length:	362	Identity:	78/362 - (21%)
Similarity:	148/362 - (40%)	Gaps:	82/362 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 KEFVAFVLGPQTLPLYKAVLITIIFGGIFITGVVGNLLVCIVIIRHSAMHTATNYYLFSLAVSDL 115
            |.||.|           :..||.....:.|..::.|:|...::.|.|...::.|..:.::|:.|:
Worm    29 KSFVTF-----------SFYITGYVYEVSILSILINILHLFILTRKSMRTSSINILMAAVALFDI 82

  Fly   116 LYLLFGLPTEVFLYWHQY-------PDLFGMPFCKIRAFI----SEACTYVSVFTIVAFSMERFL 169
            ...|..:  ::||..:.|       .|.:|:...:....:    |..|   |.:.||..::.|.|
Worm    83 FASLVHI--QLFLEQYSYLIFKCFPTDTYGLVLTRTLLIVVKDFSRRC---STWLIVFIALIRTL 142

  Fly   170 AICHPL---HLYAMVGFKRAIRIITALWIVSFISA--IPFGLLS--DIQYLNYPLD--HSRIEES 225
            .|.:||   |:  ::|..:|     :|.:::.|.|  :|..:..  :||::...:.  |...|.|
Worm   143 IIRNPLSPKHI--LLGKPKA-----SLIVIAGICAANLPISIFKFFEIQFVFVTISKHHCAPEGS 200

  Fly   226 AFCSMSPKIVNEIPVFEVSFCIFF-----------VIPMILIILLYGRMGAKIRSRTNQKLGVQQ 279
            .:...|.::......|...:..||           ::|::..:|:...:  |.|.:...::
Worm   201 YYFIASSELFLRDNGFLAKYFNFFNSFMSDMIPCILLPIVTCLLVMDLL--KTRKKCRARI---- 259

  Fly   280 GTNNRETRNSQMRKKTVIRMLAAVVITFFVCWFPFHL---QRLIFLYAKNMDNYLDINEALFSIA 341
                 ..:|:..|.||  .::..|.|.||:..|||.|   ...:|:.:..:.|.|       :..
Worm   260 -----SAKNNNSRGKT--GLVFCVAIMFFIVEFPFGLSVGSAWLFMSSPGVQNIL-------NFF 310

  Fly   342 GFAYYVSCTVNP----IVYSVMSRRYR-VAFRELLCG 373
            |:.:.|..:||.    ||..::|.:|| .|...|.||
Worm   311 GYMFTVLISVNACTHLIVCLIVSSQYRSTAISVLSCG 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	71/328 (22%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	63/308 (20%)
srw-124	NP_503810.2	7TM_GPCR_Srw	41..347	CDD:370978	70/337 (21%)
		TM helix 2	71..93	CDD:320109	4/23 (17%)
		TM helix 3	116..138	CDD:320109	5/24 (21%)
		TM helix 4	163..179	CDD:320109	3/15 (20%)
		TM helix 5	219..242	CDD:320109	3/22 (14%)
		TM helix 6	267..293	CDD:320109	11/27 (41%)
		TM helix 7	308..333	CDD:320109	6/24 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910