DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and srw-24

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_506763.2	Gene:	srw-24 / 183383	WormBaseID:	WBGene00005771	Length:	390	Species:	Caenorhabditis elegans

Alignment Length:	377	Identity:	75/377 - (19%)
Similarity:	150/377 - (39%)	Gaps:	83/377 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 TLFATSVSSDPSHGFGEEDYACGTFNCSPKEFVAFVLGPQTLPLYKAVLITIIFGGIFITGVVGN 86
            |:.|::.:.:..:||...:|........||...: :||        |:|...||  ..|..:|..
Worm     9 TIVASTANPNDYYGFVYNEYDYDFLTEQPKTRFS-ILG--------AILDFNIF--TEIVAIVLC 62

  Fly    87 LLVCIVIIRHSAMHTATNYYLFSLAVSDLLYLLFGLPTEVFLY---WHQYPDLFGMPFCKIRAFI 148
            ||..:::.|.|........::.::.:||:|.....||.:...|   |:..|            ..
Worm    63 LLHLMILFRKSLRKNGVFVFMIAICISDILNFSLALPNDSMYYKYSWYLVP------------MH 115

  Fly   149 SEACTY-----VSVFTIVAFSMERFLAICHPLH--LYAMVGFKRAIRIITALW--IVSFISAIPF 204
            .|..|:     :|::..:..::.|||::..|::  :..:|..|..:.||..:.  |:::.:|:|.
Worm   116 LEQSTFNITRRLSIWLAMVMALLRFLSVAFPMNYLIQKLVKPKNTVFIIFVVLAVIITYDAALPS 180

  Fly   205 GLLS-----DI-------QYLNYPLDHSRIEESAFCSMSPKIVNEIPVFEVSFCIFFVI-PMILI 256
            ..:|     |:       ::|.|.|..|...:....|::|   |:..|..:...:.|.: |::.|
Worm   181 LRISIAWFPDVTRCVVKSRHLRYVLIMSTDVDIDAYSITP---NQNFVERIYRVLQFTLYPLLTI 242

  Fly   257 ILLYGRMGAKIRSRTNQKLGVQQGTNNRETRNSQMRKKTVIRMLAAVVITFF----VCW------ 311
            .||......|     .::..::|..|       |:...|.: ::..:..||.    :.|
Worm   243 SLLIQLCIIK-----KKRKAMRQNEN-------QISDNTTL-LILTMTFTFMFSEGLIWIWIFID 294

  Fly   312 ----FPFHLQRLIFLYAKNMDNYLDINEALFSIAGFAYYVSCTVNPIVYSVM 359
                |.:|.. |.:........|.:|..||.    |.:.:..:::.|:.|:|
Worm   295 ADDRFYYHFD-LEYQVVSVTQEYKEILVALC----FTFRIVNSISHILVSIM 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	60/314 (19%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	58/309 (19%)
srw-24	NP_506763.2	7tm_GPCRs	49..357	CDD:391938	64/328 (20%)
		TM helix 2	79..100	CDD:341315	4/20 (20%)
		TM helix 3	114..144	CDD:341315	6/29 (21%)
		TM helix 4	158..185	CDD:341315	6/26 (23%)
		TM helix 5	218..243	CDD:341315	5/27 (19%)
		TM helix 7	302..343	CDD:341315	10/45 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910