DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CapaR and OR6B1

DIOPT Version :9

Sequence 1:	NP_996140.1	Gene:	CapaR / 40393	FlyBaseID:	FBgn0037100	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_001005281.1	Gene:	OR6B1 / 135946	HGNCID:	8354	Length:	311	Species:	Homo sapiens

Alignment Length:	329	Identity:	71/329 - (21%)
Similarity:	138/329 - (41%)	Gaps:	62/329 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 PQTLPLYKAVLITIIFGGIFITGVVGNLLVCIVIIRHSAMHTATNYYLFSLAVSDLLYLLFGLPT 124
            |.:|.:..|:.  :||...:|..|..|:::.::::::..:|....::|.:|:..:..|:...:|.
Human    18 PGSLSMRAAMF--LIFLVAYILTVAENVIIILLVLQNRPLHKPMYFFLANLSFLETWYISVTVPK 80

  Fly   125 EVFLYWHQYPDLFGMPFCKIRA--FISEACTYVSVFTIVAFSMERFLAICHPLHLYAMVGFKRAI 187
            .:|.:| ...:......|.|:.  ||:..||  ....:.|.:.:|::|||.|||...::......
Human    81 LLFSFW-SVNNSISFTLCMIQLYFFIALMCT--ECVLLAAMAYDRYVAICRPLHYPTIMSHGLCF 142

  Fly   188 RIITALWIVSF-ISAIPFGLLSDIQYLNYPLDHSRIEESAFCSMSPKI--------VNEIPVFEV 243
            |:....|.:.| ||......:|.:.:..     ..:....||.:||.:        :.|:..|.:
Human   143 RLALGSWAIGFGISLAKIYFISCLSFCG-----PNVINHFFCDISPVLNLSCTDMSITELVDFIL 202

  Fly   244 SFCIFFVIPMILIILLYGRMGAKIRSRTNQKLGVQQGTNNRETRNSQMRKKTVIRMLAAVVITFF 308
            :. :.|:.|:.:.:|.||.:.|.|......|               |....|....|  ||:|.|
Human   203 AL-VIFLFPLFITVLSYGCILATILCMPTGK---------------QKAFSTCASHL--VVVTIF 249

  Fly   309 VCWFPFHLQRLIFLYAK-------NMDNYLDINEALFSIAGFAYYVSCTVNPIVYSVMSRRYRVA 366
                   ...:||:||:       ||:..:.|         |...|:.::||.:|.:.:|..:.|
Human   250 -------YSAIIFMYARPRVIHAFNMNKIISI---------FYAIVTPSLNPFIYCLRNREVKEA 298

  Fly   367 FREL 370
            .::|
Human   299 LKKL 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tm_4	85..374	CDD:304433	64/304 (21%)
CapaR	NP_996140.1	7tm_1	85..356	CDD:278431	60/288 (21%)
OR6B1	NP_001005281.1	7tmA_OR6B-like	26..292	CDD:320352	66/309 (21%)
		TM helix 1	26..52	CDD:320352	6/27 (22%)
		TM helix 2	59..85	CDD:320352	5/25 (20%)
		TM helix 3	97..127	CDD:320352	9/31 (29%)
		TM helix 4	141..159	CDD:320352	5/17 (29%)
		TM helix 5	195..225	CDD:320352	8/30 (27%)
		TM helix 6	231..260	CDD:320352	12/52 (23%)
		TM helix 7	267..292	CDD:320352	8/33 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000