Protein Alignment CapaR and Cckbr

DIOPT Version :10

• Sequence 1: NP_996140.1
• Gene: CapaR / 40393
• FlyBaseID: FBgn0037100
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_031653.1
• Gene: Cckbr / 12426
• MGIID: 99479
• Length: 453
• Species: Mus musculus
• Alignment Length: 411
• Identity: 97/411 - (23%)
• Similarity: 161/411 - (39%)
• Gaps: 123/411 - (29%)

  Fly    42 ACGTFNC-SPKEFVAFVLGPQTLPLYKAVLITIIFGGIFITGVVGNLLVCIVIIRHSAMHTATNY 105
            :.|..:| :|:     :.|..|..|...:.|| ::..||:..|.||:|:.:|:.....:.|.||.
Mouse    33 SAGNLSCETPR-----IRGTGTRELELTIRIT-LYAVIFLMSVGGNVLIIVVLGLSRRLRTVTNA 91

  Fly   106 YLFSLAVSDLLYLLFGLPTEVFLYWHQYPDL-----FGMPFCKIRAFISEACTYVSVFTIVAFSM 165
            :|.||||||||..:..:|..:.      |:|     ||...||..:::......||...:.|.::
Mouse    92 FLLSLAVSDLLLAVACMPFTLL------PNLMGTFIFGTVICKAVSYLMGVSVSVSTLNLAAIAL 150

  Fly   166 ERFLAICHPLHLYAMVGFKRAIRIITALWIVSFISAIPFGLLSDIQYLNYPLDHSRIEESAFCSM 230
            ||:.|||.||..........|.|:|.|.|::|.:..:|:.:.:.:|                 .:
Mouse   151 ERYSAICRPLQARVWQTRSHAARVILATWLLSGLLMVPYPVYTVVQ-----------------PV 198

  Fly   231 SPKIVNEIPVFE----------VSFCIFFVIPMILIILLYGRMGAKI--------------RSRT 271
            .|:|:..:.::.          :...:.|.||.:::.:.||.:..::              :||.
Mouse   199 GPRILQCMHLWPSERVQQMWSVLLLILLFFIPGVVMAVAYGLISRELYLGLRFDGDNDSETQSRV 263

  Fly   272 NQKLG----------VQQ---------------------------------------GTNNRETR 287
            ..:.|          |.|                                       |...|..:
Mouse   264 RNQGGLPGGAAAPGPVHQNGGCRHVTSLTGEDSDGCYVQLPRSRLEMTTLTTPTTGPGPGPRPNQ 328

  Fly   288 NSQMRKKTVIRMLAAVVITFFVCWFPFHLQRLIFLYAKNMDNYLDINEALFSIAG----FAY--- 345
            ...:.||.|:|||..:|:.|||||.|        :|:.|.....|...|..::||    |.:
Mouse   329 AKLLAKKRVVRMLLVIVLLFFVCWLP--------VYSANTWRAFDGPGARRALAGAPISFIHLLS 385

  Fly   346 YVSCTVNPIVYSVMSRRYRVA 366
            |.|...||:||..|.||:|.|
Mouse   386 YTSACANPLVYCFMHRRFRQA 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CapaR	NP_996140.1	7tmA_capaR	83..367	CDD:320262	87/369 (24%)
		TM helix 2	103..129	CDD:320262	12/25 (48%)
		TM helix 3	142..172	CDD:320262	8/29 (28%)
		TM helix 4	184..206	CDD:320262	7/21 (33%)
		TM helix 5	237..266	CDD:320262	5/38 (13%)
		TM helix 6	291..321	CDD:320262	13/29 (45%)
		TM helix 7	335..360	CDD:320262	10/31 (32%)
Cckbr	NP_031653.1	7tm_GPCRs	55..407	CDD:475119	91/384 (24%)
		TM helix 1	57..81	CDD:320645	9/24 (38%)
		TM helix 2	90..112	CDD:320645	11/21 (52%)
		TM helix 3	128..150	CDD:320645	4/21 (19%)
		TM helix 4	173..189	CDD:320645	5/15 (33%)
		TM helix 5	216..239	CDD:320645	3/22 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..276		3/18 (17%)
		TM helix 6	338..360	CDD:320645	11/29 (38%)
		TM helix 7	375..400	CDD:320645	8/24 (33%)