DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rpn10 and Pip5k1c

DIOPT Version :9

Sequence 1:	NP_001262168.1	Gene:	Rpn10 / 40388	FlyBaseID:	FBgn0015283	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_001280575.1	Gene:	Pip5k1c / 18717	MGIID:	1298224	Length:	687	Species:	Mus musculus

Alignment Length:	215	Identity:	46/215 - (21%)
Similarity:	71/215 - (33%)	Gaps:	56/215 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   180 SDALLSSPIIQGEDGMGGAGLGGNVFEFGVD--PNEDPELALALRVSMEEQRQRQESEQRRANPD 242
            |.:|.|||..:|...:......|....|...  |:|..::...||.:........|     ..||
Mouse   447 SSSLKSSPSKKGRGALLAVKPLGPTAAFSASQIPSEREDVQYDLRGARSYPTLEDE-----GRPD 506

  Fly   243 GAPPTGGDAGGGGGVSGSGPGNEESAGAENEANTEEAMLQRALALSTETPEDNLPDFANMTEEEQ 307
            ..|.|              |.:.|.|...:.|.|   :...:|::...:|.|.       :|:.:
Mouse   507 LLPCT--------------PPSFEEATTASIATT---LSSTSLSIPERSPSDT-------SEQPR 547

  Fly   308 IAFAMQMSMQD--------APD-DSVTQQAKR-------PKTD---------EANAPMDVDEDYS 347
            .....|.|.||        |.| ..:|.|.:.       ||.:         .|:|...|:.|.:
Mouse   548 YRRRTQSSGQDGRPQEEPHAEDLQKITVQVEPVCGVGVVPKEEGAGVEVPPCGASAAASVEIDAA 612

  Fly   348 EVIGDPAFLQSVLENLPGVD 367
            ....:||...|..|:.|..|
Mouse   613 SQASEPASQASDEEDAPSTD 632

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpn10	NP_001262168.1	VWA_26S_proteasome_subunit	1..187	CDD:238729	3/6 (50%)
Pip5k1c	NP_001280575.1	PIPKc	103..443	CDD:214623
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910