DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7611 and PRP46

DIOPT Version :9

Sequence 1:	NP_001163489.1	Gene:	CG7611 / 40386	FlyBaseID:	FBgn0037094	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_015174.1	Gene:	PRP46 / 855952	SGDID:	S000006072	Length:	451	Species:	Saccharomyces cerevisiae

Alignment Length:	163	Identity:	40/163 - (24%)
Similarity:	70/163 - (42%)	Gaps:	44/163 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   464 DNHYRIRGYNFDSPRSDFDI--------------------LREPHPIMTFSINSADRLALLNVSN 508
            ||.:.|.|.| |:....:|:                    :.:.||.: ||::          .:
Yeast   151 DNEWFITGSN-DTTMKVWDLATGKLKTTLAGHVMTVRDVAVSDRHPYL-FSVS----------ED 203

  Fly   509 QGLHLWDIEDKCLVRRF----QGIRQSNFAIHSCFGGVNESFVASGSEDKVVYIWHIKREEPLAK 569
            :.:..||:|...::|.:    .|:|  ..:||...     ..:|:...|.|:.:|.::...|:..
Yeast   204 KTVKCWDLEKNQIIRDYYGHLSGVR--TVSIHPTL-----DLIATAGRDSVIKLWDMRTRIPVIT 261

  Fly   570 LAGHTKTVNCVSWNPVYPSLLASASDDATVRIW 602
            |.||...:|.|...||.|.:: |:|.|||||:|
Yeast   262 LVGHKGPINQVQCTPVDPQVV-SSSTDATVRLW 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7611	NP_001163489.1	CTLH	129..190	CDD:128914
		WD40	<303..605	CDD:225201	40/163 (25%)
		WD40	307..602	CDD:295369	39/161 (24%)
		WD40 repeat	318..358	CDD:293791
		WD40 repeat	364..402	CDD:293791
		WD40 repeat	410..444	CDD:293791
		WD40 repeat	448..534	CDD:293791	17/93 (18%)
		WD40 repeat	577..602	CDD:293791	12/24 (50%)
PRP46	NP_015174.1	WD40	131..427	CDD:238121	40/163 (25%)
		WD40 repeat	144..180	CDD:293791	7/29 (24%)
		WD40 repeat	186..222	CDD:293791	8/46 (17%)
		WD40 repeat	227..263	CDD:293791	8/42 (19%)
		WD40 repeat	270..305	CDD:293791	13/25 (52%)
		WD40 repeat	311..346	CDD:293791
		WD40 repeat	352..392	CDD:293791
		WD40 repeat	399..426	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000