Protein Alignment CG7611 and SPAC343.04c

DIOPT Version :9

• Sequence 1: NP_001163489.1
• Gene: CG7611 / 40386
• FlyBaseID: FBgn0037094
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_593424.1
• Gene: SPAC343.04c / 2543079
• PomBaseID: SPAC343.04c
• Length: 507
• Species: Schizosaccharomyces pombe
• Alignment Length: 524
• Identity: 166/524 - (31%)
• Similarity: 265/524 - (50%)
• Gaps: 35/524 - (6%)

  Fly    94 DKSNQEIIRLIGQYLHDVGLDKSVQTLMLESGCYLEHPSATKFREHVLMGDWSKADSDLKDLEPL 158
            :|...|:|.|:.|:|:|.|.|:|::.|..|:|...|.....:.::.||.|||..|::....:: |
pombe     5 EKFQLEVIHLLLQFLNDYGYDESLKALEKETGLVSETEDVKRLKQAVLQGDWITAEAAFSIMQ-L 68

  Fly   159 IDNGKLATITEMKFILLEQKYLEHLDDGNPLDALHVLRS-ELTPLQHNITRVHQLSSYMMCSTNQ 222
            .|..|.   .|.:|:|.:|:.||....|...:|::||:: |.|.......|   |.|.::.|.|:
pombe    69 RDESKR---KEAQFLLQKQRCLELARSGAICEAIYVLQNFESTDFNKEKER---LVSIILESNNK 127

  Fly   223 DLYQRAKWEGKGILSRALVMERLQTFMPPSVMMSPRRLRTLLQQAVELQSQHCPCHDMAWETNLE 287
            ...:.....|.| .:|..::.:|..::.|.:::..|||..|||||.:.|......|::     |:
pombe   128 SNNELITKNGYG-NTRLDLLNQLSEYISPEILLPKRRLEHLLQQAKDYQVSSQVYHNV-----LK 186

  Fly   288 TVSLLTDHCCTTDGFPMQTIQILTDHCDEVWFCKFSPDGLKLATGSKDSTVIIWDVDPYKLTLKH 352
            ..|.|:|:.......|.:...:..||.||||...:|.:|..||:.|||.|.||:||    :.||.
pombe   187 NFSFLSDYKADPSELPTKEYHVFHDHSDEVWQISYSHNGRYLASASKDKTAIIFDV----VNLKR 247

  Fly   353 RRVLDGQAQLSVSFVSWSPDSKLILVGGTEDSHELYIWNVDDGKLVVKFSQSLEDSLACGAFSRD 417
            ...|.|... :|:::.||||.:.:|....:.|  :.:|:...|:.:..:....  |::|..:..|
pombe   248 VFRLIGHID-TVAYIRWSPDDRYLLSCSCDKS--VILWDAFTGEKLRDYKHGF--SVSCCCWLPD 307

  Fly   418 GARFVCGGQKGQLYLCDLNGTIVDSWEGVRVNSIAFRAD---------NKTILAADNHYRIRGYN 473
            |..|:.|.....:....|||.|:..||.|.:..:|..:|         .:.|.|.|.|..|  |:
pombe   308 GLSFITGSPDCHITHWSLNGEILYKWEDVNIYDMALTSDGTKLYIVGFEQLINAEDKHIAI--YS 370

  Fly   474 FDSPRSDFDILREPHPIMTFSINSADRLALLNVSNQGLHLWDIEDKCLVRRFQGIRQSNFAIHSC 538
            .:: |.....:.....:.:..::...:.||.|:......|||:|:..:||::.|.:..||.|.||
pombe   371 VET-RECIKKISLQSKVTSICLSKDSKYALTNLEPHTTFLWDLEENRIVRQYMGHKLGNFLIGSC 434

  Fly   539 FGGVNESFVASGSEDKVVYIWHIKREEPLAKLAGHTKTVNCVSWNPVYPSLLASASDDATVRIWG 603
            |||.:::||.|||||..:.|||.:..:.||.|:||.|.||.|::|||.|...|||.||.|||||.
pombe   435 FGGKDDTFVLSGSEDDKIRIWHRESGKLLATLSGHVKCVNYVAYNPVDPYQFASAGDDNTVRIWS 499

  Fly   604 PKPN 607
            .|.|
pombe   500 NKDN 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7611	NP_001163489.1	CTLH	129..190	CDD:128914	17/60 (28%)
		WD40	<303..605	CDD:225201	105/310 (34%)
		WD40	307..602	CDD:295369	102/303 (34%)
		WD40 repeat	318..358	CDD:293791	16/39 (41%)
		WD40 repeat	364..402	CDD:293791	9/37 (24%)
		WD40 repeat	410..444	CDD:293791	9/33 (27%)
		WD40 repeat	448..534	CDD:293791	20/94 (21%)
		WD40 repeat	577..602	CDD:293791	15/24 (63%)
SPAC343.04c	NP_593424.1	LisH	10..38	CDD:128913	12/27 (44%)
		CTLH	40..97	CDD:128914	17/60 (28%)
		WD40	<199..506	CDD:225201	107/317 (34%)
		WD40	205..499	CDD:238121	103/305 (34%)
		WD40 repeat	216..253	CDD:293791	17/40 (43%)
		WD40 repeat	259..294	CDD:293791	8/36 (22%)
		WD40 repeat	299..335	CDD:293791	10/35 (29%)
		WD40 repeat	343..381	CDD:293791	8/40 (20%)
		WD40 repeat	386..422	CDD:293791	9/35 (26%)
		WD40 repeat	430..467	CDD:293791	18/36 (50%)
		WD40 repeat	473..498	CDD:293791	15/24 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	48	1.000	Domainoid score	I3493
eggNOG	1	0.900	-	-		E1_KOG0293
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11857
Inparanoid	1	1.050	235	1.000	Inparanoid score	I842
OMA	1	1.010	-	-		QHG54864
OrthoFinder	1	1.000	-	-		FOG0002691
OrthoInspector	1	1.000	-	-		oto100426
orthoMCL	1	0.900	-	-		OOG6_102395
Panther	1	1.100	-	-	LDO	PTHR22838
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1892
SonicParanoid	1	1.000	-	-		X1793
TreeFam	1	0.960	-	-
	14	13.860