DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cdk12 and AT1G57700

DIOPT Version :9

Sequence 1:NP_001262167.1 Gene:Cdk12 / 40385 FlyBaseID:FBgn0037093 Length:1157 Species:Drosophila melanogaster
Sequence 2:NP_176083.2 Gene:AT1G57700 / 842146 AraportID:AT1G57700 Length:692 Species:Arabidopsis thaliana


Alignment Length:473 Identity:171/473 - (36%)
Similarity:247/473 - (52%) Gaps:71/473 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   704 GARSPSPGQKKESDEKNVTSSGSANKSVLNLPMPPVIPGSEELSGDDDVIDSPED-----FDAPA 763
            |..:|. ..||:||.:..:.:|  |::.|.|     ||...:.:..|:.::..|:     |:..:
plant    24 GKENPK-ASKKQSDSEETSVNG--NEATLRL-----IPDDVKDTFSDEEVEELEEKKESSFEMKS 80

  Fly   764 VGTVHGHGG--------GPGTTRQRPVILNRRDSRNN----------------------VRDWGE 798
            ..:|...|.        ||...|     ::|..|.:|                      :..|..
plant    81 CESVLQKGNVLEIVDNVGPLQPR-----MSRIGSVSNGDRAAKVIAGWPSWLVSVAGEAINGWIP 140

  Fly   799 RCVDVFEMIAQIGEGTYGQVYKARDHHTNDMVALKKVR---LEHEKEGFPITAVREIKILRQLNH 860
            |..|.||.:..||:|||..||:|||..||.:|||||||   ::.|...|   ..|||.|||:|||
plant   141 RSADSFEKLEMIGQGTYSSVYRARDLETNQIVALKKVRFANMDPESVRF---MAREIIILRRLNH 202

  Fly   861 RNIVNLHEIVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMKQLLDGLN 925
            .|::.|..::..|.        .||.||:||||||||.||..:..:.|::......|||||.||.
plant   203 PNVMKLEGLIISKA--------SGSMYLIFEYMDHDLAGLASTPGIKFSQAQIKCYMKQLLLGLE 259

  Fly   926 YCHKKNFLHRDIKCSNILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWYRPPELLLGEER 990
            :||....|||||||||:|::....:|:.||||:..|.. .|::|.|::|:||||||||||||...
plant   260 HCHSCGVLHRDIKCSNLLLDRNNNLKIGDFGLSNFYRG-QRKQPLTSRVVTLWYRPPELLLGSTD 323

  Fly   991 YGPSIDVWSCGCILGELFVKRPLFQANAEMAQLETISKICGSPVPAVWPNVIKLPLFHT--LKQK 1053
            ||.::|:||.||||.|||..:||.....|:.|:..|.|:||||....|.   :..|.|.  .|.:
plant   324 YGVTVDLWSTGCILAELFTGKPLLPGRTEVEQMHKIFKLCGSPSEEYWR---RSRLRHATIFKPQ 385

  Fly  1054 KTHRRRLREDFEFMPAPALDLLDKMLDLDPDKRITAEDALRSPWL-RKINPDEMPTPQLPTWQDC 1117
            ..::|.:.:.|:.:|:.||.||:.:|.::||.|.||..||:|.:. .|..|.| |: .||.:|..
plant   386 HPYKRCVADTFKDLPSSALALLEVLLAVEPDARGTASSALQSEFFTTKPFPSE-PS-SLPRYQPR 448

  Fly  1118 HELWSKKRRRQMREQQES 1135
            .|..:|.|..:.|.::.|
plant   449 KEFDAKLREEEARRRKGS 466

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cdk12NP_001262167.1 STKc_CDK12 796..1098 CDD:270847 136/306 (44%)
S_TKc 804..1098 CDD:214567 133/298 (45%)
AT1G57700NP_176083.2 PKc_like 146..430 CDD:304357 133/298 (45%)
PTZ00024 152..443 CDD:240233 135/307 (44%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0600
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D925637at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24056
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.920

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