Protein Alignment Cdk12 and CDKC2

DIOPT Version :9

• Sequence 1: NP_001262167.1
• Gene: Cdk12 / 40385
• FlyBaseID: FBgn0037093
• Length: 1157
• Species: Drosophila melanogaster
• Sequence 2: NP_201301.1
• Gene: CDKC2 / 836620
• AraportID: AT5G64960
• Length: 513
• Species: Arabidopsis thaliana
• Alignment Length: 380
• Identity: 183/380 - (48%)
• Similarity: 240/380 - (63%)
• Gaps: 39/380 - (10%)

  Fly   796 WGERCVDVFEMIAQIGEGTYGQVYKARDHHTNDMVALKKVRLEHEKEGFPITAVREIKILRQLNH 860
            ||.|.||.||.:.|||||||||||.|::..|.::|||||:|:::|:|||||||:||||||::|:|
plant    18 WGSRSVDCFEKLEQIGEGTYGQVYMAKEIKTGEIVALKKIRMDNEREGFPITAIREIKILKKLHH 82

  Fly   861 RNIVNLHEIVT------DKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMKQ 919
            .|:::|.||||      |.|...:..|.||..|:|||||||||.||.:...:.|........|||
plant    83 ENVIHLKEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLADRPGLRFTVPQIKCYMKQ 147

  Fly   920 LLDGLNYCHKKNFLHRDIKCSNILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWYRPPEL 984
            ||.||:|||....||||||.||:|::|.|.:|||||||||.| :.|.....||:|||||||||||
plant   148 LLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSY-SHDHTGNLTNRVITLWYRPPEL 211

  Fly   985 LLGEERYGPSIDVWSCGCILGELFVKRPLFQANAEMAQLETISKICGSPVPAVWPNVIKLPLFHT 1049
            |||..:|||:||:||.|||..||...:|:.....|..||..|.::||||..:.||.|.|:|.::.
plant   212 LLGATKYGPAIDMWSVGCIFAELLNGKPILPGKTENEQLNKIYELCGSPDESNWPGVSKMPWYNQ 276

  Fly  1050 LKQKKTHRRRLREDFEFMPAPALDLLDKMLDLDPDKRITAEDALRSP--WLRKINPDEMP--TPQ 1110
            :|..:..:||:||.:......||:||:|||.|||.:||.|:|||.:.  |     .|.:|  ...
plant   277 MKSSRPLKRRVREIYRHFDRHALELLEKMLVLDPSQRICAKDALDAEYFW-----TDPLPCDPKS 336

  Fly  1111 LPTWQDCHELWSKKRRRQMREQQES---------------LPPTVIASTKYQQHG 1150
            |||::..||..:||:|:|||..:|:               |||        ||||
plant   337 LPTYESSHEFQTKKKRQQMRHNEEAAKKQKLQHPQQQHSRLPP--------QQHG 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk12	NP_001262167.1	STKc_CDK12	796..1098	CDD:270847	161/309 (52%)
		S_TKc	804..1098	CDD:214567	156/301 (52%)
CDKC2	NP_201301.1	STKc_CDK9_like	26..325	CDD:270832	156/299 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	309	1.000	Domainoid score	I316
eggNOG	1	0.900	-	-		E1_KOG0600
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925637at2759
OrthoFinder	1	1.000	-	-		FOG0000444
OrthoInspector	1	1.000	-	-		otm2442
orthoMCL	1	0.900	-	-		OOG6_101677
Panther	1	1.100	-	-	O	PTHR24056
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X546
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.820