DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cdk12 and AT4G22940

DIOPT Version :9

Sequence 1:	NP_001262167.1	Gene:	Cdk12 / 40385	FlyBaseID:	FBgn0037093	Length:	1157	Species:	Drosophila melanogaster
Sequence 2:	NP_001329229.1	Gene:	AT4G22940 / 828393	AraportID:	AT4G22940	Length:	560	Species:	Arabidopsis thaliana

Alignment Length:	470	Identity:	161/470 - (34%)
Similarity:	234/470 - (49%)	Gaps:	67/470 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   684 KPKSLTSLP-LPPGMNVLDLAGARSPSPGQKKESDEKNVTSSGSANKSVLNLPMPPVIPGSEELS 747
            ||.:.|.|| ..|..:.|         |.:::.::::       |.|....|.|...: |.:||.
plant    11 KPAAPTGLPENRPRFHTL---------PSERRIANDQ-------AQKVTELLKMSDKL-GPKELK 58

  Fly   748 GDDDVI---DSPEDFDAPAVG------TVHGH---GGGPGTTRQRPVILNRRDSRNNVRDWGERC 800
            .::.::   ..|...:..|.|      :|.|.   |..||           |:|.
plant    59 REESILVVNVHPRSSELAASGWPPWLISVAGEALVGWTPG-----------RESH---------- 102

  Fly   801 VDVFEMIAQIGEGTYGQVYKARDHHTNDMVALKKVRLE-HEKEGFPITAVREIKILRQLNHRNIV 864
               ||...|||.||:.:|:||||...|..||||::|.: :..|.....| |||.|||:|:|.|::
plant   103 ---FEKQEQIGGGTFSKVFKARDLLRNKTVALKRIRFDINNSESIKCIA-REIIILRKLDHPNVI 163

  Fly   865 NLHEIVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMKQLLDGLNYCHK 929
            .|..::....|:       .:.||:||||:|||:||.....|.|:|......|:|||.||::||.
plant   164 KLEGLMLVDHDS-------STLYLIFEYMEHDLLGLSSLLGVHFSEPQVKCYMRQLLRGLDHCHT 221

  Fly   930 KNFLHRDIKCSNILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWYRPPELLLGEERYGPS 994
            .:.||||:|.||:|:|..|.:|:||||||..::..: ..|.|..|.||||||||||||...||..
plant   222 NHVLHRDMKSSNLLINGDGVLKIADFGLATFFDPHN-SVPLTTHVATLWYRPPELLLGASHYGIG 285

  Fly   995 IDVWSCGCILGELFVKRPLFQANAEMAQLETISKICGSPVPAVWPNVIKLPLFHTLKQKKTHRRR 1059
            :|:||.||::|||:..:|:.....|..||..|.|:||||....|.. :||.|...|:....:...
plant   286 VDLWSTGCVIGELYAGKPILPGKNETDQLHKIFKLCGSPSDDYWTK-LKLQLSTPLRPIYPYGSH 349

  Fly  1060 LREDFEFMPAPALDLLDKMLDLDPDKRITAEDALRSPWLRKINPDEMPTPQLPTWQDCHELWSKK 1124
            :.|.|:..||..:.||:.:|.:|||.|.||..||:|.:. |..|.......||.:....|: :.|
plant   350 IAETFKQFPASVISLLETLLSIDPDFRGTAASALKSKYF-KTEPLACDPSCLPKYPSSKEI-NIK 412

  Fly  1125 RRRQMREQQESLPPT 1139
            .|...|:|...:..|
plant   413 MRDNTRKQASQIRRT 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cdk12	NP_001262167.1	STKc_CDK12	796..1098	CDD:270847	126/302 (42%)
Cdk12	NP_001262167.1	S_TKc	804..1098	CDD:214567	126/294 (43%)
AT4G22940	NP_001329229.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0600
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925637at2759
OrthoFinder	1	1.000	-	-		FOG0000444
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24056
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920