DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cdk12 and AT3G01085

DIOPT Version :9

Sequence 1:	NP_001262167.1	Gene:	Cdk12 / 40385	FlyBaseID:	FBgn0037093	Length:	1157	Species:	Drosophila melanogaster
Sequence 2:	NP_001325617.1	Gene:	AT3G01085 / 821283	AraportID:	AT3G01085	Length:	631	Species:	Arabidopsis thaliana

Alignment Length:	466	Identity:	153/466 - (32%)
Similarity:	226/466 - (48%)	Gaps:	58/466 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   685 PKSLTSLPLPPG-MNVLDLAGARSPSPGQKKESDEKNVTSSGSANKSVL---NLPMPPVIPGSEE 745
            |.:...||.||. ..|::    .||...:..:.|.....::|.:.:|.|   |:....|..|
plant    34 PHNRHVLPGPPSHRRVVN----SSPKKHRNNDDDAPKSRTTGVSLRSGLPHSNVEAEQVAAG--- 91

  Fly   746 LSGDDDVIDSPEDFDAPAVGTVHGHGGGPGTTRQRPVILNRRDSRNNVRDWGERCVDVFEMIAQI 810
                     .|....:.|...|||                          |.....:.||...:|
plant    92 ---------WPSWLSSAAPEAVHG--------------------------WVPLRAEDFEKREKI 121

  Fly   811 GEGTYGQVYKARDHHTNDMVALKKVRLEH-EKEGFPITAVREIKILRQLNHRNIVNLHEIVTDKQ 874
            |:|||..|::|.:..|..::||||:|::: |.|.....| |||.|||:|:|.||:.|..|:..
plant   122 GQGTYSNVFRACEVSTGRVMALKKIRIQNFETENIRFIA-REIMILRRLDHPNIMKLEGIIAS-- 183

  Fly   875 DAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMKQLLDGLNYCHKKNFLHRDIKC 939
                  ::..|.|.||:||:|||.||..|..:.|.|......|||||.|:.:||.:..:|||||.
plant   184 ------RNSNSMYFVFDYMEHDLEGLCSSPDIKFTEAQIKCYMKQLLWGVEHCHLRGIMHRDIKA 242

  Fly   940 SNILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWYRPPELLLGEERYGPSIDVWSCGCIL 1004
            :|||:||:|.:||||||||.:....::.: .|::|:|||||.||||:|...|..|:|:||.||:.
plant   243 ANILVNNKGVLKLADFGLANIVTPRNKNQ-LTSRVVTLWYRAPELLMGSTSYSVSVDLWSVGCVF 306

  Fly  1005 GELFVKRPLFQANAEMAQLETISKICGSPVPAVWPNVIKLPLFHTLKQKKTHRRRLREDFEFMPA 1069
            .|:...|||.:...|:.||..|.|:.|||....|......|.....:.:..:...|||.|:..|.
plant   307 AEILTGRPLLKGRTEIEQLHKIYKLSGSPDEEFWEKNKLHPQTKMFRPQHQYEGCLRERFDEFPK 371

  Fly  1070 PALDLLDKMLDLDPDKRITAEDALRSPWLRKINPDEMPTPQLPTWQDCHELWSKKRRRQMREQQE 1134
            .|::||:.:|.:||:||.||..||.|.:. ...|.......||.:....|:.:|.|....|.::.
plant   372 TAINLLENLLSIDPEKRGTASSALMSEYF-NTQPYACDPSTLPKYPPNKEMDAKYREELQRRRRV 435

  Fly  1135 SLPPTVIASTK 1145
            |:......:||
plant   436 SIKKRDNLATK 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cdk12	NP_001262167.1	STKc_CDK12	796..1098	CDD:270847	123/302 (41%)
Cdk12	NP_001262167.1	S_TKc	804..1098	CDD:214567	122/294 (41%)
AT3G01085	NP_001325617.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0600
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925637at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24056
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920