Protein Alignment Cdk12 and cdk1

DIOPT Version :10

• Sequence 1: NP_649325.2
• Gene: Cdk12 / 40385
• FlyBaseID: FBgn0037093
• Length: 1157
• Species: Drosophila melanogaster
• Sequence 2: NP_997729.1
• Gene: cdk1 / 80973
• ZFINID: ZDB-GENE-010320-1
• Length: 302
• Species: Danio rerio
• Alignment Length: 316
• Identity: 129/316 - (40%)
• Similarity: 190/316 - (60%)
• Gaps: 21/316 - (6%)

  Fly   801 VDVFEMIAQIGEGTYGQVYKARDHHTNDMVALKKVRLEHEKEGFPITAVREIKILRQLNHRNIVN 865
            :|.:..|.:|||||||.|||.|:..|..:||:||:|||.|:||.|.||||||.:|::|.|.|:|.
Zfish     1 MDDYLKIEKIGEGTYGVVYKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKELQHPNVVR 65

  Fly   866 LHEIVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMK----QLLDGLNY 926
            |.:::          ..:...|||||::..||...|:|  :...|..:..::|    |:|:|:.:
Zfish    66 LLDVL----------MQESKLYLVFEFLSMDLKKYLDS--IPSGEFMDPMLVKSYLYQILEGILF 118

  Fly   927 CHKKNFLHRDIKCSNILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWYRPPELLLGEERY 991
            ||.:..||||:|..|:|::|:|.:|||||||||.:...  .|.||::|:|||||.||:|||..||
Zfish   119 CHCRRVLHRDLKPQNLLIDNKGVIKLADFGLARAFGVP--VRVYTHEVVTLWYRAPEVLLGASRY 181

  Fly   992 GPSIDVWSCGCILGELFVKRPLFQANAEMAQLETISKICGSPVPAVWPNVIKLPLF-HTLKQKKT 1055
            ...:|:||.|.|..||..|:|||..::|:.||..|.:..|:|...|||:|..||.: :|..:.|:
Zfish   182 STPVDLWSIGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNEVWPDVESLPDYKNTFPKWKS 246

  Fly  1056 HRRRLREDFEFMPAPALDLLDKMLDLDPDKRITAEDALRSPWLRKINPDEMPTPQL 1111
              ..|....:.:....:|||.|||..||.|||:|..|:..|:...::...:|...|
Zfish   247 --GNLANTVKNLDKNGIDLLMKMLIYDPPKRISARQAMTHPYFDDLDKSSLPASNL 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk12	NP_649325.2	STKc_CDK12	796..1098	CDD:270847	127/301 (42%)
cdk1	NP_997729.1	STKc_CDK1_euk	3..287	CDD:270845	126/299 (42%)