Protein Alignment Cdk12 and cdk10

DIOPT Version :10

• Sequence 1: NP_649325.2
• Gene: Cdk12 / 40385
• FlyBaseID: FBgn0037093
• Length: 1157
• Species: Drosophila melanogaster
• Sequence 2: NP_001017622.2
• Gene: cdk10 / 550285
• ZFINID: ZDB-GENE-050417-94
• Length: 360
• Species: Danio rerio
• Alignment Length: 314
• Identity: 134/314 - (42%)
• Similarity: 189/314 - (60%)
• Gaps: 14/314 - (4%)

  Fly   799 RCVDVFEMIAQIGEGTYGQVYKARDHHTNDMVALKKVRLEHEKEGFPITAVREIKILRQLNHRNI 863
            |.|..||.|.:|||||||.||:|||..||::|||||||::.||:|.||:::|||.:|.:|.|.||
Zfish    35 RSVKEFEKINRIGEGTYGIVYRARDTRTNEIVALKKVRMDKEKDGIPISSLREINLLIRLRHPNI 99

  Fly   864 VNLHEIVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMKQLLDGLNYCH 928
            |.|.|:|....  :|      |.:||..|.:.||..|||:....|:|.....|:.|||.||.|.|
Zfish   100 VELKEVVVGSH--LE------SLFLVMSYCEQDLASLLENMQSPFSEAQVKCIVLQLLKGLAYLH 156

  Fly   929 KKNFLHRDIKCSNILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWYRPPELLLGEERYGP 993
            ....||||:|.||:||.::|.||:|||||||:|...  .:|.|.:|:|||||.||||||.:....
Zfish   157 HNFILHRDLKVSNLLMTDKGCVKIADFGLARVYGIP--LQPMTPRVVTLWYRAPELLLGTKTQTT 219

  Fly   994 SIDVWSCGCILGELFVKRPLFQANAEMAQLETISKICGSPVPAVWPNVIKLPLFHTLKQKKTHRR 1058
            ::|:|:.|||..||...:||....:|:.||:.|.::.|:|..::||...:|||......:|....
Zfish   220 ALDMWAVGCIFAELLAHKPLLPGASEIQQLDLIVQLLGTPNESIWPGFSRLPLVGQYSLRKQPYN 284

  Fly  1059 RLREDFEFMPAPALDLLDKMLDLDPDKRITAEDALRSPWLRK----INPDEMPT 1108
            .|:..|.::....|.||:.:...:|.:|.||.|.|.|.:.::    ..|:.|||
Zfish   285 NLKNKFTWLSEAGLRLLNLLFMYNPQRRATAIDCLESSYFKEKPLPCEPELMPT 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk12	NP_649325.2	STKc_CDK12	796..1098	CDD:270847	130/298 (44%)
cdk10	NP_001017622.2	STKc_CDK10	32..340	CDD:173742	134/314 (43%)