Protein Alignment Cdk12 and Cdk1

DIOPT Version :10

• Sequence 1: NP_649325.2
• Gene: Cdk12 / 40385
• FlyBaseID: FBgn0037093
• Length: 1157
• Species: Drosophila melanogaster
• Sequence 2: NP_062169.1
• Gene: Cdk1 / 54237
• RGDID: 2319
• Length: 297
• Species: Rattus norvegicus
• Alignment Length: 301
• Identity: 128/301 - (42%)
• Similarity: 186/301 - (61%)
• Gaps: 31/301 - (10%)

  Fly   807 IAQIGEGTYGQVYKARDHHTNDMVALKKVRLEHEKEGFPITAVREIKILRQLNHRNIVNLHEIVT 871
            |.:|||||||.|||.|...|..:||:||:|||.|:||.|.||:|||.:|::|.|.|||:|.:::
  Rat     7 IEKIGEGTYGVVYKGRHRTTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVL- 70

  Fly   872 DKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMK----QLLDGLNYCHKKNF 932
             .||:        ..||:||::..||...|:|  :...:..::|::|    |:|.|:.:||.:..
  Rat    71 -MQDS--------RLYLIFEFLSMDLKKYLDS--IPPGQFMDSSLVKSYLYQILQGIVFCHSRRV 124

  Fly   933 LHRDIKCSNILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWYRPPELLLGEERYGPSIDV 997
            ||||:|..|:|::::|.:|||||||||.:...  .|.||::|:|||||.||:|||..||...:|:
  Rat   125 LHRDLKPQNLLIDDKGTIKLADFGLARAFGIP--IRVYTHEVVTLWYRSPEVLLGSARYSTPVDI 187

  Fly   998 WSCGCILGELFVKRPLFQANAEMAQLETISKICGSPVPAVWPNVIKLPLF-HTLKQKK-----TH 1056
            ||.|.|..||..|:|||..::|:.||..|.:..|:|...|||.|..|..: :|..:.|     :|
  Rat   188 WSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASH 252

  Fly  1057 RRRLREDFEFMPAPALDLLDKMLDLDPDKRITAEDALRSPW 1097
            .:.|.|:       .||||.|||..||.|||:.:.||:.|:
  Rat   253 VKNLDEN-------GLDLLSKMLVYDPAKRISGKMALKHPY 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk12	NP_649325.2	STKc_CDK12	796..1098	CDD:270847	128/301 (43%)
Cdk1	NP_062169.1	STKc_CDK1_euk	3..287	CDD:270845	128/301 (43%)