| Sequence 1: | NP_001262167.1 | Gene: | Cdk12 / 40385 | FlyBaseID: | FBgn0037093 | Length: | 1157 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_057591.2 | Gene: | CDK12 / 51755 | HGNCID: | 24224 | Length: | 1490 | Species: | Homo sapiens |
| Alignment Length: | 1179 | Identity: | 437/1179 - (37%) |
|---|---|---|---|
| Similarity: | 591/1179 - (50%) | Gaps: | 235/1179 - (19%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 11 LVEYSDVSSED--FSDQEAGDLDA---DAGKGAGNIKKPKPAPDNQFSKGR--LDAKPDKEGYDN 68
Fly 69 YRSRRAEDSSDPVAAGSRQTSSSEATNPREEPSQASNTSKDELWGREIYMSSDSIDTDELEAEMK 133
Fly 134 RQKRKKQKKEKHKHKSKKKSKKRKKKRAKSYSSIDSMSDNDINALLDRRYTPPTAPSKSNERTVS 198
Fly 199 AAPSSFTPHNLKESSSPATPPPVRRPNTNSNYYGESSLETANSALGSNLQVTVTNKQSISNRLRS 263
Fly 264 PPPSSRSSGNGPRFGNSPRTPPPSHYSSSGGGGVGSGSVVRDSRSSRYVNSPHKEDVSAHHRSSH 328
Fly 329 DHGYQGRYSGAGSSSHDTRKVKRLSPELDRYNHQPSTPPHKRRKFSDGREVGLGNFEHSRHHSGK 393
Fly 394 YERYSRDRYSRRSSRSPSVQHSRSRQSPSGGLSSGSNAFRHGGSHKHKYGTTVSSTPSHTTRTSK 458
Fly 459 RASGTGTSGDRYSRSPRTSSRYMESSPPSPVGASGSHHYHHRRSPRMRQRTRGDSRRRSPSSASS 523
Fly 524 ESSASRSR----SPTSRDLKHKREEYIKKISETSLFAELVKD------RHKRQKALKEIIERQEE 578
Fly 579 NSNSNSNGALTINDNSSSVDGNTPNAADGRSAPGSGTPAAASTTSNGLQ-----------ALGSK 632
Fly 633 PDL-------------DLNNIPMPNKQNDSVVSNPASNADVPDSVAQLKQPLLVPPFSASKNNIK 684
Fly 685 PKSLTSLPLP---PGMNVLDLAGARSPSPGQKKESDEKNVTSSGSANKSVLNLPMPPVIPGSEEL 746
Fly 747 SGDDDVIDSPEDFDAPAVGTVHGHGGGPGTT--RQRPVILNRR--DSRNNVRDWGERCVDVFEMI 807
Fly 808 AQIGEGTYGQVYKARDHHTNDMVALKKVRLEHEKEGFPITAVREIKILRQLNHRNIVNLHEIVTD 872
Fly 873 KQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMKQLLDGLNYCHKKNFLHRDI 937
Fly 938 KCSNILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWYRPPELLLGEERYGPSIDVWSCGC 1002
Fly 1003 ILGELFVKRPLFQANAEMAQLETISKICGSPVPAVWPNVIKLPLFHTLKQKKTHRRRLREDFEFM 1067
Fly 1068 PAPALDLLDKMLDLDPDKRITAEDALRSPWLRKINPDEMPTPQLPTWQDCHELWSKKRRRQMRE- 1131
Fly 1132 -QQESLPPT 1139 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Cdk12 | NP_001262167.1 | STKc_CDK12 | 796..1098 | CDD:270847 | 226/301 (75%) |
| S_TKc | 804..1098 | CDD:214567 | 220/293 (75%) | ||
| CDK12 | NP_057591.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..703 | 183/816 (22%) | |
| STKc_CDK12 | 719..1020 | CDD:270847 | 226/301 (75%) | ||
| S_TKc | 727..1020 | CDD:214567 | 220/293 (75%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1047..1098 | 7/17 (41%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1161..1189 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1220..1348 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1441..1460 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1466..1490 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 465 | 1.000 | Domainoid score | I471 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG0600 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 590 | 1.000 | Inparanoid score | I992 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D925637at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000444 | |
| OrthoInspector | 1 | 1.000 | - | - | otm40905 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_101677 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR24056 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R186 |
| SonicParanoid | 1 | 1.000 | - | - | X546 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 13 | 12.860 | |||||