Protein Alignment Cdk12 and Cdk2

DIOPT Version :9

• Sequence 1: NP_001262167.1
• Gene: Cdk12 / 40385
• FlyBaseID: FBgn0037093
• Length: 1157
• Species: Drosophila melanogaster
• Sequence 2: NP_001163666.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Alignment Length: 318
• Identity: 130/318 - (40%)
• Similarity: 186/318 - (58%)
• Gaps: 26/318 - (8%)

  Fly   801 VDVFEMIAQIGEGTYGQVYKARDHHTNDMVALKKVRLEHEKEGFPITAVREIKILRQLNHRNIVN 865
            :|.|:...:|||||||.|||||.:.|...|||||:|||.|.||.|.||:|||.:|:.|.|.|:|.
  Fly     5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQ 69

  Fly   866 LHEIVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMKQLLDGLNYCHKK 930
            |.::|.          ...:.|::|||::.||..|::.....|..:...|.|.|:||.:.:||..
  Fly    70 LFDVVI----------SGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTN 124

  Fly   931 NFLHRDIKCSNILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWYRPPELLLGEERYGPSI 995
            ..||||:|..|:|::..||:|||||||||.:|..  .|.||::|:|||||.||:|||.:.|...:
  Fly   125 RILHRDLKPQNLLVDTAGKIKLADFGLARAFNVP--MRAYTHEVVTLWYRAPEILLGTKFYSTGV 187

  Fly   996 DVWSCGCILGELFVKRPLFQANAEMAQLETISKICGSPVPAVWPNVIKLPLFHTLKQKKTHRRRL 1060
            |:||.|||..|:.::|.||..::|:.||..|.:...:|....||.|.:||.|.|        :..
  Fly   188 DIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKT--------KFP 244

  Fly  1061 REDFEFMPAP-----ALDLLDKMLDLDPDKRITAEDALRSPWLRKI-NPDEMPTPQLP 1112
            |.:...||.|     |.:|:..||..||:.||:|:|||:..:.|.: :.|.:..|..|
  Fly   245 RWEGTNMPQPITEHEAHELIMSMLCYDPNLRISAKDALQHAYFRNVQHVDHVALPVDP 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk12	NP_001262167.1	STKc_CDK12	796..1098	CDD:270847	126/301 (42%)
		S_TKc	804..1098	CDD:214567	125/298 (42%)
Cdk2	NP_001163666.1	PLN00009	5..293	CDD:177649	127/307 (41%)
		STKc_CDK1_CdkB_like	8..287	CDD:270829	125/298 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442460
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24056
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940