Protein Alignment Cdk12 and Cdk5

DIOPT Version :9

• Sequence 1: NP_001262167.1
• Gene: Cdk12 / 40385
• FlyBaseID: FBgn0037093
• Length: 1157
• Species: Drosophila melanogaster
• Sequence 2: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Alignment Length: 302
• Identity: 122/302 - (40%)
• Similarity: 178/302 - (58%)
• Gaps: 28/302 - (9%)

  Fly   804 FEMIAQIGEGTYGQVYKARDHHTNDMVALKKVRLEHEKEGFPITAVREIKILRQLNHRNIVNLHE 868
            ::.:.:|||||||.|:|.|:..|.::||||:|||:.:.||.|.:|:|||.:|::|.|:|||.|.:
  Fly     4 YDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNIVRLID 68

  Fly   869 IV-TDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMKQLLDGLNYCHKKNF 932
            :: :||:           ..||||:.|.||....:|...:.:.....|.|.|||.||.:||..|.
  Fly    69 VLHSDKK-----------LTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNV 122

  Fly   933 LHRDIKCSNILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWYRPPELLLGEERYGPSIDV 997
            ||||:|..|:|:|..|::|||||||||.:...  .:.|:.:|:|||||||::|.|.:.|..|||:
  Fly   123 LHRDLKPQNLLINKNGELKLADFGLARAFGIP--VKCYSAEVVTLWYRPPDVLFGAKLYTTSIDM 185

  Fly   998 WSCGCILGELF-VKRPLFQANAEMAQLETISKICGSPVPAVWPNV------IKLPLFHTLKQKKT 1055
            ||.||||.||. ..||||..:..:.||..|.::.|:|....||.|      :.||.|..:.....
  Fly   186 WSAGCILAELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVALPSFPAITSWSQ 250

  Fly  1056 HRRRLREDFEFMPAPALDLLDKMLDLDPDKRITAEDALRSPW 1097
            ...||.       :...|||.|:|...|::||:||.|::.|:
  Fly   251 LVPRLN-------SKGRDLLQKLLICRPNQRISAEAAMQHPY 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk12	NP_001262167.1	STKc_CDK12	796..1098	CDD:270847	122/302 (40%)
		S_TKc	804..1098	CDD:214567	122/302 (40%)
Cdk5	NP_477080.1	PLN00009	1..288	CDD:177649	122/302 (40%)
		STKc_CDK5	3..286	CDD:143344	122/302 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442469
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24056
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940