Protein Alignment Cdk12 and Pk34A

DIOPT Version :10

• Sequence 1: NP_649325.2
• Gene: Cdk12 / 40385
• FlyBaseID: FBgn0037093
• Length: 1157
• Species: Drosophila melanogaster
• Sequence 2: NP_609603.1
• Gene: Pk34A / 34705
• FlyBaseID: FBgn0028410
• Length: 392
• Species: Drosophila melanogaster
• Alignment Length: 330
• Identity: 91/330 - (27%)
• Similarity: 145/330 - (43%)
• Gaps: 54/330 - (16%)

  Fly   810 IGEGTYGQVYKARDHHTNDMVALKKVRLEHEKEGFPITAVREIKILRQL-NHRNIVNL--HEIVT 871
            ||.|::|:||:|..:.:.::||:|:....      |..:..|.:|:.|| :|.|||.|  |..|:
  Fly    50 IGSGSFGRVYQAHVNESEEIVAVKQTLYN------PKLSQGEAEIMGQLKDHNNIVRLIMHSSVS 108

  Fly   872 DKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEEN---NASIMK-QLLDGLNYCHKKNF 932
            ....:|::      ..||.|||...|:..:...:.......   |..|:. |:..||.|.|....
  Fly   109 LGFPSVDY------VLLVMEYMPMTLLDYINYHLTVLQPAERLINVRILSYQMFRGLGYLHLLGI 167

  Fly   933 LHRDIKCSNILMNNRGKV-KLADFGLARLYNADDRERPYTNKVITLWYRPPELLLGEERYGPSID 996
            .|||:|..|:|::|:..| ||:|||.|:|...   :.|..:.:.:..||.|||..|.|.|..::|
  Fly   168 SHRDVKPENLLIDNQKMVLKLSDFGSAKLLVP---QEPSISYICSRLYRAPELFAGYELYSCAVD 229

  Fly   997 VWSCGCILGELFVKRPLFQANA-EMAQLETISKICGSPVPAVWPNVIKLPLFHTLKQKKTHRRRL 1060
            :||.||:|.||....|||.::. :..||..|..:.|:      ..:.:.|...:......|.|..
  Fly   230 IWSAGCVLAELLKGYPLFSSHKHDRKQLRLIVNMLGT------DGLERAPEILSKCGNSLHPRTT 288

  Fly  1061 REDFEFM-----PAPALDLLDKMLDLDPDKRIT--------------AEDALRSPWLRKINPDEM 1106
            |..:.::     |.....||:.....:...||:              ..||:..|.     |:..
  Fly   289 RPSWNYLLNTAVPQDLCGLLNSCFIYEAAARISPMMACSHGSYDELRIMDAMALPM-----PNGN 348

  Fly  1107 PTPQL 1111
            |.|.|
  Fly   349 PLPPL 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk12	NP_649325.2	STKc_CDK12	796..1098	CDD:270847	87/315 (28%)
Pk34A	NP_609603.1	STKc_GSK3	39..334	CDD:271039	84/304 (28%)