Protein Alignment Cdk12 and cdk11

DIOPT Version :10

• Sequence 1: NP_649325.2
• Gene: Cdk12 / 40385
• FlyBaseID: FBgn0037093
• Length: 1157
• Species: Drosophila melanogaster
• Sequence 2: NP_595739.1
• Gene: cdk11 / 2540799
• PomBaseID: SPBC18H10.15
• Length: 398
• Species: Schizosaccharomyces pombe
• Alignment Length: 314
• Identity: 130/314 - (41%)
• Similarity: 183/314 - (58%)
• Gaps: 18/314 - (5%)

  Fly   801 VDVFEMIAQIGEGTYGQVYKARDHHTNDMVALKKVRLEHEKEGFPITAVREIKILRQLNHRNIVN 865
            :|.:|::.:|.||:||.||:..|..||.:|||||::.:....|||||::|||:.|..:.|.|||.
pombe    71 IDDYEILEKIEEGSYGIVYRGLDKSTNTLVALKKIKFDPNGIGFPITSLREIESLSSIRHDNIVE 135

  Fly   866 LHEIVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMKQLLDGLNYCHKK 930
            |.::|..        ||....|||.|:|:|||..||::...||.:....::|.|||....:.|..
pombe   136 LEKVVVG--------KDLKDVYLVMEFMEHDLKTLLDNMPEDFLQSEVKTLMLQLLAATAFMHHH 192

  Fly   931 NFLHRDIKCSNILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWYRPPELLLGEERYGPSI 995
            .:||||:|.||:||||.|::|||||||||  ...:.:...|..|:|||||.||||||...||..|
pombe   193 WYLHRDLKPSNLLMNNTGEIKLADFGLAR--PVSEPKSSLTRLVVTLWYRAPELLLGAPSYGKEI 255

  Fly   996 DVWSCGCILGELFVKRPLFQANAEMAQLETISKICGSPVPAVWPNVIKLPLFHTLKQK--KTHRR 1058
            |:||.|||..|:..:.|||...:|:.||..|..:.|.|....||....||..:.:|..  .|| .
pombe   256 DMWSIGCIFAEMITRTPLFSGKSELDQLYKIFNLLGYPTREEWPQYFLLPYANKIKHPTVPTH-S 319

  Fly  1059 RLREDFEFMPAPALDLLDKMLDLDPDKRITAEDALRSPWLRKINPDEMPTPQLP 1112
            ::|.....:...|.|||:::|.|:|.|||:|::||..|:..     |.|.|:.|
pombe   320 KIRTSIPNLTGNAYDLLNRLLSLNPAKRISAKEALEHPYFY-----ESPRPKDP 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk12	NP_649325.2	STKc_CDK12	796..1098	CDD:270847	126/298 (42%)
cdk11	NP_595739.1	STKc_CDC2L1	68..359	CDD:173741	126/298 (42%)