Protein Alignment Cdk12 and Cdk10

DIOPT Version :9

• Sequence 1: NP_001262167.1
• Gene: Cdk12 / 40385
• FlyBaseID: FBgn0037093
• Length: 1157
• Species: Drosophila melanogaster
• Sequence 2: NP_919428.1
• Gene: Cdk10 / 234854
• MGIID: 2448549
• Length: 360
• Species: Mus musculus
• Alignment Length: 314
• Identity: 136/314 - (43%)
• Similarity: 187/314 - (59%)
• Gaps: 14/314 - (4%)

  Fly   799 RCVDVFEMIAQIGEGTYGQVYKARDHHTNDMVALKKVRLEHEKEGFPITAVREIKILRQLNHRNI 863
            |.|..||.:.:|||||||.||:|||..|:::|||||||::.||:|.||:::|||.:|.:|.|.||
Mouse    34 RSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNI 98

  Fly   864 VNLHEIVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMKQLLDGLNYCH 928
            |.|.|:|....  :|      |.:||..|.:.||..|||:....|:|.....||.|:|.||.|.|
Mouse    99 VELKEVVVGNH--LE------SIFLVMGYCEQDLASLLENMPTPFSEAQVKCIMLQVLRGLQYLH 155

  Fly   929 KKNFLHRDIKCSNILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWYRPPELLLGEERYGP 993
            :...:|||:|.||:||.::|.||.|||||||.|...  .:|.|.||:|||||.||||||......
Mouse   156 RNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVP--VKPMTPKVVTLWYRAPELLLGTTTQTT 218

  Fly   994 SIDVWSCGCILGELFVKRPLFQANAEMAQLETISKICGSPVPAVWPNVIKLPLFHTLKQKKTHRR 1058
            |||:|:.||||.||...:||....:|:.|::.|.::.|:|...:||...||||......:|....
Mouse   219 SIDMWAVGCILAELLAHKPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLAGQYSLRKQPYN 283

  Fly  1059 RLREDFEFMPAPALDLLDKMLDLDPDKRITAEDALRSPWLRK----INPDEMPT 1108
            .|:..|.::....|.||:.:...||.||.|:.|.|.|.:.::    ..|:.|||
Mouse   284 NLKHKFPWLSEAGLRLLNFLFMYDPKKRATSGDCLESSYFKEKPLPCEPELMPT 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk12	NP_001262167.1	STKc_CDK12	796..1098	CDD:270847	132/298 (44%)
		S_TKc	804..1098	CDD:214567	130/293 (44%)
Cdk10	NP_919428.1	STKc_CDK10	31..339	CDD:173742	136/314 (43%)
		PTZ00024	43..336	CDD:240233	129/302 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	334..360		3/4 (75%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925637at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920