Protein Alignment Cdk12 and cdk-1

DIOPT Version :10

• Sequence 1: NP_649325.2
• Gene: Cdk12 / 40385
• FlyBaseID: FBgn0037093
• Length: 1157
• Species: Drosophila melanogaster
• Sequence 2: NP_001022747.1
• Gene: cdk-1 / 176374
• WormBaseID: WBGene00000405
• Length: 332
• Species: Caenorhabditis elegans
• Alignment Length: 318
• Identity: 122/318 - (38%)
• Similarity: 180/318 - (56%)
• Gaps: 27/318 - (8%)

  Fly   804 FEMIAQIGEGTYGQVYKARDHHTNDMVALKKVRLEHEKEGFPITAVREIKILRQLNHRNIVNLHE 868
            |..:.:|||||||.|||.::..||.|||:||:|||.|.||.|.||||||.:|::|.|.|:|.|..
 Worm    22 FTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQHPNVVGLEA 86

  Fly   869 IVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLES-GMVDFNE-ENNASIMKQLLDGLNYCHKKN 931
            ::          ..:...:|:||::..||...::. |..::.. |...|...|:|..:.:||::.
 Worm    87 VI----------MQENRLFLIFEFLSFDLKRYMDQLGKDEYLPLETLKSYTFQILQAMCFCHQRR 141

  Fly   932 FLHRDIKCSNILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWYRPPELLLGEERYGPSID 996
            .:|||:|..|:|::|.|.:|||||||||.....  .|.||::|:|||||.||:|:|.:||...:|
 Worm   142 VIHRDLKPQNLLVDNNGAIKLADFGLARAIGIP--IRVYTHEVVTLWYRAPEILMGAQRYSMGVD 204

  Fly   997 VWSCGCILGELFVKRPLFQANAEMAQLETISKICGSPVPAVWPNVIKLPLFHTLKQKKTHRRRLR 1061
            :||.|||..|:..|:||||.::|:.:|..|.::.|:|....|..|..||.:.. ...|.....||
 Worm   205 MWSIGCIFAEMATKKPLFQGDSEIDELFRIFRVLGTPTELEWNGVESLPDYKA-TFPKWRENFLR 268

  Fly  1062 EDF-------EFMPAPALDLLDKMLDLDPDKRITAEDALRSPWLRKINPDEMPTPQLP 1112
            :.|       ..:...|..||:.:|..||..|:.|:.||..|:.     |.|.|.:||
 Worm   269 DKFYDKKTGKHLLDDTAFSLLEGLLIYDPSLRLNAKKALVHPYF-----DNMDTSKLP 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk12	NP_649325.2	STKc_CDK12	796..1098	CDD:270847	117/302 (39%)
cdk-1	NP_001022747.1	STKc_CDK1_euk	21..312	CDD:270845	117/302 (39%)