Protein Alignment Cdk12 and cdk-7

DIOPT Version :10

• Sequence 1: NP_649325.2
• Gene: Cdk12 / 40385
• FlyBaseID: FBgn0037093
• Length: 1157
• Species: Drosophila melanogaster
• Sequence 2: NP_001370652.1
• Gene: cdk-7 / 171784
• WormBaseID: WBGene00000408
• Length: 330
• Species: Caenorhabditis elegans
• Alignment Length: 338
• Identity: 120/338 - (35%)
• Similarity: 187/338 - (55%)
• Gaps: 35/338 - (10%)

  Fly   804 FEMIAQIGEGTYGQVYKARDHHTNDMVALKKVRL---EHEKEGFPITAVREIKILRQLNHRNIVN 865
            ::.|..:|||.:..||.|:|..:.:.||:||::|   |..|:|...||:||||:|::::|.||:.
 Worm     5 YDTIKHLGEGQFANVYLAQDLESGECVAIKKIKLGSREEAKDGINRTAIREIKLLKEIHHDNIIG 69

  Fly   866 LHEIVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMKQLLDGLNYCHKK 930
            |.:::..:.          |..|||::||.||..:::...:.....:..:|..|:|.||.:.|..
 Worm    70 LRDVIGHRT----------SIQLVFDFMDTDLEHVIKDKEIILMPAHIKNITMQMLLGLEFLHVH 124

  Fly   931 NFLHRDIKCSNILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWYRPPELLLGEERYGPSI 995
            ..||||:|.:|:|||..|:|||.||||||.:.:.:|.  ||::|:|.|||.||||.|...||..|
 Worm   125 WILHRDLKPNNLLMNKMGRVKLTDFGLARFFGSPNRN--YTHQVVTRWYRAPELLFGARSYGVGI 187

  Fly   996 DVWSCGCILGELFVKRPLFQANAEMAQLETISKICGSPVPAVWPNVIKLPLFHTLKQKKTHRRRL 1060
            |:||.|||:.||.::.|:|...:::.||..|..|.|.|.|..|||:.::..:..:| .:|....|
 Worm   188 DIWSVGCIIAELLLRNPIFPGESDIDQLVKIFNILGCPTPETWPNMTEMNSYVIIK-PQTEYMAL 251

  Fly  1061 REDFEFMPAPALDLLDKMLDLDPDKRITAEDALRSPWLRKINP-----DEMPTPQLPTWQDCHEL 1120
            ...|...|...|||:..|...||.||:|...:|:..:.| ..|     :|:|.|
 Worm   252 NYYFSAAPQDLLDLMAGMWTFDPIKRLTCTQSLQMEYFR-TQPFCCLDEELPLP----------- 304

  Fly  1121 WSKKRRRQMREQQ 1133
              ||::.|.|.::
 Worm   305 --KKQQPQKRSRR 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk12	NP_649325.2	STKc_CDK12	796..1098	CDD:270847	111/296 (38%)
cdk-7	NP_001370652.1	STKc_CDK7	4..302	CDD:270833	114/310 (37%)