Protein Alignment Cdk12 and Cdc10

DIOPT Version :10

• Sequence 1: NP_649325.2
• Gene: Cdk12 / 40385
• FlyBaseID: FBgn0037093
• Length: 1157
• Species: Drosophila melanogaster
• Sequence 2: XP_315879.5
• Gene: Cdc10 / 1276521
• VectorBaseID: AGAMI1_004285
• Length: 403
• Species: Anopheles gambiae
• Alignment Length: 362
• Identity: 140/362 - (38%)
• Similarity: 212/362 - (58%)
• Gaps: 28/362 - (7%)

  Fly   780 RPVILNRRDSRNNVRD-----------WGE-RCVDVFEMIAQIGEGTYGQVYKARDHHTNDMVAL 832
            |||  :|:....|.|.           :|: |.|..|:...::||||||.|::|||..:|::|||
Mosquito    13 RPV--HRKGMLMNFRTKEYTEIRPQDVYGKCRYVSSFQKCNRVGEGTYGIVFRARDTVSNEIVAL 75

  Fly   833 KKVRLEHE--KEGFPITAVREIKILRQLNHRNIVNLHEIVTDKQDAVEFRKDKGSFYLVFEYMDH 895
            |||||:.:  |:||||:.:|||:||:..:|.|||.|.|:|..  :::|      |.:||.|:.:.
Mosquito    76 KKVRLDQDIFKDGFPISGLREIQILKNCSHENIVRLKEVVVG--NSLE------SIFLVMEFCEQ 132

  Fly   896 DLMGLLESGMVDFNEENNASIMKQLLDGLNYCHKKNFLHRDIKCSNILMNNRGKVKLADFGLARL 960
            ||..||::....|:|.....|:.|||.||:|.|.:..:|||:|.||:|:.:.|.:|:|||||||.
Mosquito   133 DLASLLDNMETPFSESQVKCIIIQLLKGLDYLHTRYIIHRDLKVSNLLLTDTGCLKIADFGLARY 197

  Fly   961 YNADDRERPYTNKVITLWYRPPELLLGEERYGPSIDVWSCGCILGELFVKRPLFQANAEMAQLET 1025
            .|  :..:|.|..::||||||||||.|.::...::|:|:.|||||||.:.:||....:|::|:|.
Mosquito   198 LN--NANKPMTPGLVTLWYRPPELLFGAKKQTTAVDMWATGCILGELLIHKPLLPGTSEISQIEL 260

  Fly  1026 ISKICGSPVPAVWPNVIKLPLFHTLKQKKTHRRRLREDFEFMPAPALDLLDKMLDLDPDKRITAE 1090
            |..:.|:|...:||:...|||......|:.....|:..|.|:.|...|||:.:...:|..|.|||
Mosquito   261 IINLLGTPTATIWPDFDSLPLVQNFTLKEQPYNNLKSKFPFLSASGYDLLNSLFMYNPACRATAE 325

  Fly  1091 DALRSPWLRK--INPDEMPTPQLPTWQDCHELWSKKR 1125
            ..|.|.:||:  :..|....|..|..:|..:..|.|:
Mosquito   326 RCLLSTYLREPPLPCDSNLMPTFPHHRDMKKTTSAKQ 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk12	NP_649325.2	STKc_CDK12	796..1098	CDD:270847	126/304 (41%)
Cdc10	XP_315879.5	None