Protein Alignment SAK and Plk2

DIOPT Version :9

• Sequence 1: NP_649324.1
• Gene: SAK / 40384
• FlyBaseID: FBgn0026371
• Length: 769
• Species: Drosophila melanogaster
• Sequence 2: NP_114009.1
• Gene: Plk2 / 83722
• RGDID: 620760
• Length: 682
• Species: Rattus norvegicus
• Alignment Length: 582
• Identity: 148/582 - (25%)
• Similarity: 245/582 - (42%)
• Gaps: 163/582 - (28%)

  Fly    19 LLGKGGFATVYKARCLHTHQDVAIKMIDKKLIQGTGLTNRVRQEVEIHSRLKHPSVLQLYTFFQD 83
            :|||||||..|:...|..::..|.|:|....:.......::.:|:|:|..|.|..|:|.|.:|:|
  Rat    84 VLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFED 148

  Fly    84 ANYVYLVLELAHNGELHRYMNHIARP---FTETEAASILKQVVAGLLYLHSHNIMHRDISLSNLL 145
            ...:|::||...    .|.|.||.:.   .||.|....|:|:|:||.|||...|:|||:.|.|..
  Rat   149 KENIYILLEYCS----RRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFF 209

  Fly   146 LSREMHVKIADFGLATQLKRPDERHMTMCGTPNYISPEVVSRTSHGLPADVWSVGCMLYTLLVGR 210
            ::..|.:|:.|||||.:|:..:.|..|:||||||:||||:::..||..:|:|::||::||:|:||
  Rat   210 INEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGR 274

  Fly   211 PPFETDAVQSTLNKVVMSEYIMPAHLSYEAQDLINKLLKKLPHERITLEAVLCHPFMLK------ 269
            |||||..::.|...:..:.|.||:.|...|:.||..:|.|.|.:|.:|:.::.|.|.|:
  Rat   275 PPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDR 339

  Fly   270 -CSNGGHSAPG------ALNVFSQSMESGDSGIITFASSDSRNSQQIRSVENSGPQQVLPQIREE 327
             .|:..|:.|.      |.|.|.::..:...|                           .:.:..
  Rat   340 LSSSCCHTVPDFHLSSPAKNFFKKAAAALFGG---------------------------KKDKAR 377

  Fly   328 FKQVHHKLPYEQTGLFGQASTGLAEPNWPGAAKSSAFCMEAGNVPNSKQASLKEDRISVPPLNTK 392
            :...|:|:..|...::                              ..:..||:..|:..
  Rat   378 YNDTHNKVSKEDEDIY------------------------------KLRHDLKKTSITQQ----- 407

  Fly   393 RLLPTRYKTKNAIM----SILRNGEVVLEFLKFRPTYNEDRINDICR------------------ 435
               |::::|...:.    :..::|...:|        |:.:|.|..|
  Rat   408 ---PSKHRTDEELQPPPTTFAKSGTSAVE--------NKQQIGDAIRMIVRGTLGSCSSSSECLE 461

  Fly   436 ------ISDDGQRIIIYQPDPGRGLPVREQPPDLQ-IPSGDCVYNYDNLPSKHW--------KKY 485
                  ::|...|::       ||.        |: :|..||:.......|..|        .||
  Rat   462 DSTMGSVADTVARVL-------RGC--------LENMPEADCIPKEQLSTSFQWVTKWVDYSNKY 511

  Fly   486 IYGARF----VG-----------LVKSKTPKVTYFSTLGKCQLMETMTDFEIRFYSGAKLLK 532
            .:|.:.    ||           |...||  |.|::.||:|.:... ||...:|.|...:||
  Rat   512 GFGYQLSDHTVGVLFNNGAHMSLLPDKKT--VHYYAELGQCSVFPA-TDAPEQFISQVTVLK 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SAK	NP_649324.1	STKc_PLK4	12..267	CDD:271088	96/250 (38%)
		S_TKc	14..267	CDD:214567	96/250 (38%)
		POLO_box_Plk4_1	382..497	CDD:240557	25/166 (15%)
		POLO_box_Plk4_2	498..596	CDD:240558	13/35 (37%)
		POLO_box_Plk4_3	657..738	CDD:240559
Plk2	NP_114009.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	25..67
		STKc_PLK2	77..331	CDD:271090	96/250 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	402..430		4/35 (11%)
		POLO_box_1	500..585	CDD:240561	20/74 (27%)
		POLO_box_2	598..679	CDD:240560

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0575
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D507604at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820