Protein Alignment SAK and plk3

DIOPT Version :10

• Sequence 1: NP_649324.1
• Gene: SAK / 40384
• FlyBaseID: FBgn0026371
• Length: 769
• Species: Drosophila melanogaster
• Sequence 2: NP_001006766.1
• Gene: plk3 / 448451
• XenbaseID: XB-GENE-5860546
• Length: 661
• Species: Xenopus tropicalis
• Alignment Length: 589
• Identity: 150/589 - (25%)
• Similarity: 232/589 - (39%)
• Gaps: 198/589 - (33%)

  Fly    14 YEVQHLLGKGGFATVYKARCLHTHQDVAIKMIDKKLIQGTGLTNRVRQEVEIHSRLKHPSVLQLY 78
            |....||||||||..|:...:.|::..|:|:|....:.......::..|:::|..|.|..|::..
 Frog    60 YTKGRLLGKGGFARCYEMTEVATNKTYAVKVIPHSRVAKPHQREKIVNEIDLHRELHHKHVVKFS 124

  Fly    79 TFFQDANYVYLVLELAHNGELHRYMNHI--AR-PFTETEAASILKQVVAGLLYLHSHNIMHRDIS 140
            ..|:|:..:|:.||:..    .:.:.||  || ...|.|....|||:::||.|||...|:|||:.
 Frog   125 HHFEDSENIYIFLEICS----RKSLAHIWKARHTLLEPEVRYFLKQIISGLKYLHLKGILHRDLK 185

  Fly   141 LSNLLLSREMHVKIADFGLATQLKRPDERHMTMCGTPNYISPEVVSRTSHGLPADVWSVGCMLYT 205
            |.|..::..|.:|:.|||||.:|:.|::|..|:||||||::|||:.|..||..:|:||:||::||
 Frog   186 LGNFFINESMELKVGDFGLAARLEPPEQRKKTICGTPNYLAPEVLYRQGHGPESDIWSLGCVMYT 250

  Fly   206 LLVGRPPFETDAVQSTLNKVVMSEYIMPAHLSYEAQDLINKLLKKLPHERITLEAVLCHPFMLK- 269
            ||.|.|||||..::.|...:...:|.:||.||..|:.|:..:||:.|.||:||:.:|.|.|..|
 Frog   251 LLCGTPPFETSDLKETYRCIKQVKYTLPACLSSAAKHLLMGILKRTPGERLTLDQILEHEFFTKG 315

  Fly   270 ----------------------------------------------------------------- 269
                                                                             
 Frog   316 YTPDKLPPSSCVMVPDLHPPNPAKSLFTKVAKSLFGKTKSKTKKSPTEEKDDISKIVTGLVKTSI 380

  Fly   270 CS-------NGGHSAP------------------------------GALNVFSQSMES--GDSGI 295
            |.       :|...||                              |:|...|.:.|.  ..||:
 Frog   381 CRQLSYKTVDGNEVAPVTSHAVSANSSPVDTLTEEASGKSVSRSIRGSLVSSSDAFEDCVTASGV 445

  Fly   296 ITFASS---DSRNS--------------------------------------QQIRSVENSGPQQ 319
            |..|.:   ||.:|                                      :.|..:.|||...
 Frog   446 IETALAVLKDSLSSMPAVEGNPTSLAKPEHFVWVSKWVDYSNKYGFGYQLSNRSIGVLFNSGTHM 510

  Fly   320 VLPQIREEFKQVHHKLPYEQTGLF----------GQAS-----TGLAEPNWPGAAKSSAFCMEAG 369
            |||..|   :.||:.|...:..:|          ||.|     ....|.|          .|:.|
 Frog   511 VLPAHR---RHVHYNLTNSRHFVFPTSAVPEQLQGQMSILQYFATYMEKN----------LMKGG 562

  Fly   370 NVPNSKQASLKEDRISVPPLNTKRLLPTRYKTKNAIMSILRNGEVVLEFLKFRPTYNEDRINDIC 434
            ::|..::.|           .|..||....||::|::.:..||.:.:.|      ||:.....:|
 Frog   563 DLPCHEEGS-----------QTPLLLLQWVKTEHALLMLFSNGTLQVNF------YNDHTKIILC 610

  Fly   435 RISD 438
            :..|
 Frog   611 KPQD 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SAK	NP_649324.1	STKc_PLK4	12..267	CDD:271088	99/255 (39%)
		POLO_box_Plk4_1	382..497	CDD:240557	13/57 (23%)
		POLO_box_Plk4_2	498..596	CDD:240558
		POLO_box_Plk4_3	657..738	CDD:240559
plk3	NP_001006766.1	STKc_PLK3	58..312	CDD:271091	99/255 (39%)
		POLO_box_1	477..563	CDD:240561	18/98 (18%)
		POLO_box_2	577..658	CDD:240560	11/44 (25%)