Protein Alignment SAK and Plk5

DIOPT Version :9

• Sequence 1: NP_649324.1
• Gene: SAK / 40384
• FlyBaseID: FBgn0026371
• Length: 769
• Species: Drosophila melanogaster
• Sequence 2: XP_006240983.1
• Gene: Plk5 / 314627
• RGDID: 1305038
• Length: 614
• Species: Rattus norvegicus
• Alignment Length: 589
• Identity: 150/589 - (25%)
• Similarity: 226/589 - (38%)
• Gaps: 157/589 - (26%)

  Fly    14 YEVQHLLGKGGFATVYKARCLHTHQDVAIKMIDKKLIQGTG---LTNRVRQEVEIHSRLKHPSVL 75
            |....|:|||.|:..||...:.|....|:|::.:   .|.|   |..:|.:|:.:||||.|.:::
  Rat    27 YRRGKLIGKGAFSRCYKLTDMSTSAVFALKVVPR---GGAGRLRLRGKVEREIALHSRLHHRNIV 88

  Fly    76 QLYTFFQDANYVYLVLELAHNGELHRYMNHIARPFTETEAASILKQVVAGLLYLHSHNIMHRDIS 140
            ..:..|.|.::||:|||......|...:. :.|..||.|.....:.:|:||.|||...|:|||:.
  Rat    89 AFHAHFADRDHVYMVLEYCSRQSLAHVLK-VRRTLTEPEVRYYFRGLVSGLRYLHQQRIVHRDLK 152

  Fly   141 LSNLLLSREMHVKIADFGLATQLKRPDERHMTMCGTPNYISPEVVSRTSHGLPADVWSVGCMLYT 205
            .||..|::.|.|||.|.|||.::......|..:|||||:.:||||||..|...:|:|::||::||
  Rat   153 PSNFFLNKNMEVKIGDLGLAARVGPAGRCHRVLCGTPNFQAPEVVSRNGHSAKSDIWALGCIMYT 217

  Fly   206 LLVGRPPFETDAVQSTLNKVVMSEYIMPAHLSYEAQDLINKLLKKLPHERITLEAVLCHPFMLKC 270
            :|.|.|||....:......:....|:.|..||..|:.||.:||...|.||.:|:.:|...|.
  Rat   218 VLTGTPPFAAAPLSEMYQNIRDGHYLEPTQLSPSARSLIARLLAPDPDERPSLDHLLQDDFF--- 279

  Fly   271 SNG----------GHSAPGALNVFSQSMESGDSGIITFASSDSRNSQQIRSVENSGPQQVLPQIR 325
            |.|          .||.|                :..|.                      |.:.
  Rat   280 SQGFTPERLPPHSCHSPP----------------VFAFP----------------------PPLG 306

  Fly   326 EEFKQVHHKLPYEQTGLFGQASTGLAEPNWPGAAKSSAFCMEAGNVPNSKQAS-------LKEDR 383
            ..|::|            ||.......|..|..:|.::...|....|:..:||       ..|.|
  Rat   307 RLFRKV------------GQLLLTQCRPPCPFTSKEASGPGEESTEPDHMEASNEEGAPLCTESR 359

  Fly   384 ISVPPLNTKRLLPTRYKTKNAIMSILRNGEVVLEFLKFRPTYNEDRINDICRISDDG-------- 440
            |.:..|.|.|..|...|           |.:.|:.        |.....:|...|.|
  Rat   360 IHLLTLGTPRTDPADAK-----------GTLALQL--------EVATRKLCLCLDAGPVGRTATP 405

  Fly   441 ---------------------QRIIIYQP----------------DPGRGLPVRE-QPPDLQIPS 467
                                 ||.:::.|                |.|.|:..|: ....|:.|.
  Rat   406 KCRTEAAWRGPKPAGQDPPGEQRSVLWAPKWVDYSLKYGFGYQLSDGGSGVLFRDGSHMALRPPG 470

  Fly   468 GDCVYNYDNLPSKHWKKYIYGARFV-GLVKSKTPKVTYFSTLGKCQLMETMTDFEIRFYSGAKLL 531
            |...|..|.  ...|   |:..|.| |.:::|...:..|:...:.:|.|..|         |.:.
  Rat   471 GHVSYQPDQ--GTLW---IFALRDVPGPLRAKLAVLRLFACYMQRRLREEGT---------APMT 521

  Fly   532 KTPS 535
            .||:
  Rat   522 ATPA 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SAK	NP_649324.1	STKc_PLK4	12..267	CDD:271088	92/255 (36%)
		S_TKc	14..267	CDD:214567	92/255 (36%)
		POLO_box_Plk4_1	382..497	CDD:240557	30/161 (19%)
		POLO_box_Plk4_2	498..596	CDD:240558	8/38 (21%)
		POLO_box_Plk4_3	657..738	CDD:240559
Plk5	XP_006240983.1	STKc_PLK	25..279	CDD:271001	92/255 (36%)
		S_TKc	27..279	CDD:214567	92/255 (36%)
		POLO_box_1	429..516	CDD:240561	19/91 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0575
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D507604at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820