Protein Alignment SAK and plo1

DIOPT Version :9

• Sequence 1: NP_649324.1
• Gene: SAK / 40384
• FlyBaseID: FBgn0026371
• Length: 769
• Species: Drosophila melanogaster
• Sequence 2: NP_593647.1
• Gene: plo1 / 2541957
• PomBaseID: SPAC23C11.16
• Length: 683
• Species: Schizosaccharomyces pombe
• Alignment Length: 709
• Identity: 161/709 - (22%)
• Similarity: 286/709 - (40%)
• Gaps: 172/709 - (24%)

  Fly    20 LGKGGFATVYKARCLHTHQD----VAIKMIDKKLIQGTGLTNRVRQEVEIHSRLKHPSVLQLYTF 80
            :|:|||     |||.....:    .|.|:|.|:.:|......::..|:::|..:.||:::.....
pombe    47 IGEGGF-----ARCFRVKDNYGNIYAAKVIAKRSLQNDKTKLKLFGEIKVHQSMSHPNIVGFIDC 106

  Fly    81 FQDANYVYLVLELAHNGELHRYMNHIARPFTETEAASILKQVVAGLLYLHSHNIMHRDISLSNLL 145
            |:|:..:||:|||..:..|...:.. .:..||.|...::.|::..|.|:|...::|||:.|.|::
pombe   107 FEDSTNIYLILELCEHKSLMELLRK-RKQLTEPEVRYLMMQILGALKYMHKKRVIHRDLKLGNIM 170

  Fly   146 LSREMHVKIADFGLATQLKRPDERHMTMCGTPNYISPEVV--SRTSHGLPADVWSVGCMLYTLLV 208
            |....:|||.|||||..|...:||.||:|||||||:||::  |:..|....|:||.|.::|.||:
pombe   171 LDESNNVKIGDFGLAALLMDDEERKMTICGTPNYIAPEILFNSKEGHSFEVDLWSAGVVMYALLI 235

  Fly   209 GRPPFETDAVQSTLNKVVMSEYIMPAH--LSYEAQDLINKLLKKLPHERITLEAVLCHPFMLKCS 271
            |:|||:...|::...|:..:.|..|::  :|.||:|||:.||...|..|.:::.::.|.|.
pombe   236 GKPPFQDKEVKTIYRKIKANSYSFPSNVDISAEAKDLISSLLTHDPSIRPSIDDIVDHEFF---- 296

  Fly   272 NGGHSAPGALNVFSQSMESGDSGIITFASSDSRNSQQIRSVENSGPQQVLPQIREEFKQVHHKLP 336
            :.|:.|....:....||.       .:.||.|::|.| |:::
pombe   297 HTGYMASTLPDEILHSMP-------IWPSSQSKSSFQ-RNLD----------------------- 330

  Fly   337 YEQTGLFGQASTGLAEPNWPGAAKSSAFCMEAGNVPNSKQASLKEDRISVPPLNTKRLLPTRYKT 401
                  |..:::|:...|..|..|:..:.:....|.|.                  |:||:....
pombe   331 ------FVASASGVGFGNSAGVEKNKPYALRTDEVDND------------------RILPSVLSP 371

  Fly   402 KNAIMSILRNGEVVLEFLKFRPTYNEDRINDICRISDD--GQRIIIYQPDPGRGLP----VREQP 460
            ::.:..:::.|...    |..|:.....::...:.:|.  |.|:.:.:.:....:|    |.||.
pombe   372 RDRVNPVMKIGPET----KPVPSKLSTALHAARKSTDGSLGSRVKVLREESQSFVPTKSAVTEQV 432

  Fly   461 PDLQI---PSGDCVYNYD---NLPSKHWKKYIYGARFVGL-VKSKTPKVTYFSTLGKCQLMET-M 517
            ..:|:   .|.:.|....   |:.|..|......|..:|: :::.|..:|......:..|..| .
pombe   433 EPIQLIRSLSANTVSRLSKVGNMKSDIWISVKKTALKIGMALEAHTHALTSEDADSEPVLFITKW 497

  Fly   518 TDFEIRFYSGAKLLKTPSEGLKVYDRNGMLLSDYSCSESRSLIEHGNECFTHCVNISNALEVAQT 582
            .|:..::..|.: |...|.|:...|...:|.     |....::|:                ....
pombe   498 VDYSNKYGLGYQ-LSDESVGVHFNDDTSLLF-----SADEEVVEY----------------ALHP 540

  Fly   583 KDNSCFPVTIGRRPITDVQPAQRL-DGLRDTTNI-------------------AFSTPKSNQGSI 627
            ||....|.         :.||.:: :.:|....:                   :|..||
pombe   541 KDTEIKPY---------IYPASKVPESIRSKLQLLKHFKSYMGQNLSKAVQDESFEKPK------ 590

  Fly   628 NFSLSTISSTRNTSDFGTNCSRSNMLAAHQNIPIKRINVPEIGIATELSHGVVQVQFYD 686
                   :||.||..|..:..|:..                 .|...||:|:.|..|.|
pombe   591 -------NSTSNTMLFMQHYLRTRQ-----------------AIMFRLSNGIFQFNFLD 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SAK	NP_649324.1	STKc_PLK4	12..267	CDD:271088	87/254 (34%)
		S_TKc	14..267	CDD:214567	87/254 (34%)
		POLO_box_Plk4_1	382..497	CDD:240557	21/127 (17%)
		POLO_box_Plk4_2	498..596	CDD:240558	16/98 (16%)
		POLO_box_Plk4_3	657..738	CDD:240559	7/30 (23%)
plo1	NP_593647.1	STKc_PLK	41..296	CDD:271001	87/254 (34%)
		S_TKc	41..296	CDD:214567	87/254 (34%)
		POLO_box_1	490..580	CDD:240561	17/120 (14%)
		POLO_box_2	599..676	CDD:240560	9/44 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0575
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24345
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910