Protein Alignment SAK and zyg-1

DIOPT Version :9

• Sequence 1: NP_649324.1
• Gene: SAK / 40384
• FlyBaseID: FBgn0026371
• Length: 769
• Species: Drosophila melanogaster
• Sequence 2: NP_495103.1
• Gene: zyg-1 / 173956
• WormBaseID: WBGene00006988
• Length: 706
• Species: Caenorhabditis elegans
• Alignment Length: 791
• Identity: 189/791 - (23%)
• Similarity: 304/791 - (38%)
• Gaps: 170/791 - (21%)

  Fly     2 LSNRAFGETIEDYEVQHLLGKGGFATVYKARCLHTHQDVAIKMIDKKLIQGTGLTNRVRQEVEIH 66
            :|....|..:..|.....:|||||..||.|: ....:.||||.||||:.:     |||..|::..
 Worm     1 MSGGKSGSRLSAYSHLKEIGKGGFGVVYAAQ-RENGEKVAIKRIDKKVPK-----NRVWTEIQTM 59

  Fly    67 SRLKHPS-VLQLYTFFQDANYVYLVLELAHNGELHRYM-NHIARPFTETEAASILKQVVAGLLYL 129
            ..||... |::.|..|.:..|.|:|:||...|.|..|: .|.|  ..:..|..:|:|:::.:.::
 Worm    60 KELKKSKYVVEFYEDFVEDGYTYIVMELCEGGSLQAYVREHGA--LDDATAVHVLRQLISAVSFM 122

  Fly   130 HSHNIMHRDISLSNLLL----SREMHVKIADFGLATQLKRPDERHMTMCGTPNYISPEVVSRTSH 190
            |..|::|||:|..|:.:    .::|.||:.||||||.|.| .|...|:.|||.:|:|:|..: .:
 Worm   123 HRVNVIHRDLSAGNVFIKDSKKKKMTVKLGDFGLATTLGR-GETTCTIVGTPGFIAPQVYDQ-EY 185

  Fly   191 GLPADVWSVGCMLYTLLVGRPPFETDAVQSTLNKVVMSEYIMPAHLSYEAQDLINKLLKKLPHER 255
            ...|||:|:|.:|||:|..|.| ....:..|..            :|..|..|:.:::.....:|
 Worm   186 TQSADVYSLGAVLYTMLTARNP-PPKGLPPTCG------------MSPNAARLVEQMMDTDAKKR 237

  Fly   256 ITLEAVLCHPFMLKCSNGG-------HSAPGALNVFSQSMESGDSGIITFASSDSRNSQQIRSVE 313
            |.|..::...||.:.:|..       ||..|......:.:.|         |.|.|:......:.
 Worm   238 IPLTQIVLSEFMYENTNENAVIFSREHSRDGRRQRSREPVRS---------SRDDRSRDGRALIR 293

  Fly   314 NSGPQQVLPQIREEFKQVHHKLPYEQTGLFGQASTGLAEPNWPGAAKSSAFCMEAGNVPNSKQAS 378
            :|.......:.....:.:|.::|       ..:|.|..........:.|.    .|.||.|
 Worm   294 SSSQPAHSGRAPLSNRPIHDRMP-------STSSRGFDSERGRERDRDSG----RGTVPPS---- 343

  Fly   379 LKEDRISVPPLNTKRLLPTRYKTKNAIMSILRNGEVVLEFLKFRPTYNEDRINDICRISDDGQ-- 441
             :|||      |..:|.|.|.............|..::|            ::..||.....|
 Worm   344 -REDR------NRSQLWPIRMDRLEGQRVCTAGGRYIVE------------LDTRCRFEVAAQGN 389

  Fly   442 ---RIIIYQPD-----------PGRGLPVREQPPDL-QIPSGDCVY-NYDNLPSKHWKKYIYGAR 490
               ||:|.:.|           |.|.:..|....:| .:.:...|| :|..:|.:....|:...:
 Worm   390 FVKRILIVEVDEMVQTVYVHRIPDRTVRGRNGEEELITLTNNPFVYTSYSQMPKEVQNDYMRLQK 454

  Fly   491 FVGL-VKSKTPKVTY-----FSTLGKCQLMETMTDFEIRFYSGAKLLKTPSEGLKVYDRNGMLLS 549
            .|.: :..:..|||:     |.. .:.||||          :|...:|.|...:.....||.:
 Worm   455 MVAVTISGRVAKVTFRRPSQFPD-AQAQLME----------NGDLRIKLPRSVIVRKMDNGEI-- 506

  Fly   550 DYSCSE---------SRSLIEHGNECFTHCVNISNALEVAQTKDNSCFPVT-------IGRRPIT 598
             ::|.:         |...:...||.:.:.:.....|. ...:...|||:.       :|..| :
 Worm   507 -FNCIDGIATQKQAVSGITLTKVNEVYKYLIRFEQCLN-GMDRGMVCFPIVFSAGTNMVGSSP-S 568

  Fly   599 DVQPAQRLDGLRDTTNIAFSTPKSNQGSI-----NFSLSTISSTRNTSDFGTNCSR-------SN 651
            .:.|:    |...|:...||...:||.|:     .|.....||.|.:|   .|..|       |:
 Worm   569 SLMPS----GSSQTSRFPFSNLSNNQPSLVPHSAPFLTKPTSSQRASS---ANVQRRVSTDENSS 626

  Fly   652 MLAAHQNIPIKRINVPEIGIATELSHGVVQVQFYDGSVVSVIPSMQGGGITYTQPNGTSTHFGKG 716
            ...|.....||      |...|:   .|..:|..||.|:....| :.....:|.|      ..:.
 Worm   627 PSVAPSKYKIK------IDPTTQ---KVRSIQATDGRVLRCSTS-KADQFIFTDP------AIRP 675

  Fly   717 DDLPFPVRDRV 727
            ||..|...|||
 Worm   676 DDQRFMRTDRV 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SAK	NP_649324.1	STKc_PLK4	12..267	CDD:271088	83/260 (32%)
		S_TKc	14..267	CDD:214567	83/258 (32%)
		POLO_box_Plk4_1	382..497	CDD:240557	25/133 (19%)
		POLO_box_Plk4_2	498..596	CDD:240558	22/118 (19%)
		POLO_box_Plk4_3	657..738	CDD:240559	18/71 (25%)
zyg-1	NP_495103.1	S_TKc	13..249	CDD:214567	83/258 (32%)
		PKc_like	13..238	CDD:304357	80/247 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910