Protein Alignment SAK and LOC1268576

DIOPT Version :10

• Sequence 1: NP_649324.1
• Gene: SAK / 40384
• FlyBaseID: FBgn0026371
• Length: 769
• Species: Drosophila melanogaster
• Sequence 2: XP_061497547.1
• Gene: LOC1268576 / 1268576
• VectorBaseID: AGAMI1_002184
• Length: 702
• Species: Anopheles gambiae
• Alignment Length: 684
• Identity: 307/684 - (44%)
• Similarity: 407/684 - (59%)
• Gaps: 107/684 - (15%)

  Fly     7 FGETIEDYEVQHLLGKGGFATVYKARCLHTHQDVAIKMIDKKLIQGTGLTNRVRQEVEIHSRLKH 71
            |||.||:|||..:||||||..|||||||.:...||||||||..:..:|:.|||||||.|||:|||
Mosquito     5 FGEKIEEYEVGEILGKGGFGCVYKARCLISGNSVAIKMIDKHAMHASGMANRVRQEVAIHSKLKH 69

  Fly    72 PSVLQLYTFFQDANYVYLVLELAHNGELHRYMNHIARPFTETEAASILKQVVAGLLYLHSHNIMH 136
            ||:|::||||:|.|:||||||||.||||.:|:....:||:|.|||.||::||.||.|||||.|:|
Mosquito    70 PSILEMYTFFEDFNFVYLVLELAENGELQQYLKQRIQPFSEFEAAMILRKVVDGLFYLHSHRILH 134

  Fly   137 RDISLSNLLLSREMHVKIADFGLATQLKRPDERHMTMCGTPNYISPEVVSRTSHGLPADVWSVGC 201
            ||||||||||::||::|||||||||||.|.||:|:|:|||||||||||.||.|||||||||.:||
Mosquito   135 RDISLSNLLLTKEMNIKIADFGLATQLHRSDEKHLTLCGTPNYISPEVASRASHGLPADVWGLGC 199

  Fly   202 MLYTLLVGRPPFETDAVQSTLNKVVMSEYIMPAHLSYEAQDLINKLLKKLPHERITLEAVLCHPF 266
            ||||||||:|||:|:.|:|||.:||:|.|::|.|||.:..|||.:||:|.|.|||.||.||.|||
Mosquito   200 MLYTLLVGKPPFDTNGVKSTLARVVLSNYVLPVHLSSDVSDLIERLLRKNPAERIKLEEVLSHPF 264

  Fly   267 MLKCSNGGHSAPGALNVFSQSMESG-DSGIITFASS------------------DSRNSQQIR-- 310
            :.:...|..:|..::|..:....|| |||:.|.|.|                  |.|:..|.:
Mosquito   265 LSRYDLGHKTAINSMNATNNKFNSGMDSGMGTIAGSSVSKSDLFNGNRGMTQANDRRSDHQKQDL 329

  Fly   311 ------------------SVENSGPQQVLP----QIREEFKQVH--HKLPYEQTGLFGQAST-GL 350
                              .:||....:..|    .:.|:|..|.  ||....:..|.....| .|
Mosquito   330 NGEKFTLVHPYWKQMHQYEIENMSSYRFQPNSQISLLEKFNSVELVHKYNIIEDKLIENDKTKNL 394

  Fly   351 AE----PNWPGAAKSSAFC--------------------------------------MEAGNVPN 373
            .|    .::.|..|.:..|                                      ..:|.|||
Mosquito   395 YELKPSTDFLGMKKETEVCNPQQYISRRYVTPVSDRSIHEQINHGHVTSENKNNNMHKASGFVPN 459

  Fly   374 SKQASLKEDRISVPPLNTKRLLPTRYKTKNAIMSIL-RNGEVVLEFLKFRPTYNEDRINDICRIS 437
            :.:.:::.|        |.||||||::||:.|::|: ..|:|||||||.|....|||:.|:||||
Mosquito   460 NHRHTMRFD--------TLRLLPTRHRTKHVILTIVAEGGDVVLEFLKPRGRQREDRVVDVCRIS 516

  Fly   438 DDGQRIIIYQPDPGRGLPVREQPPDLQIPSGDCVYNYDNLPSKHWKKYIYGARFVGLVKSKTPKV 502
            .||.:.|:|.|:..||:|::.:||||...|.:.:|||:::|.||:|||:|.|:||.:||:||||:
Mosquito   517 GDGLKFILYHPNGNRGVPIKNEPPDLPSRSAEVMYNYEDIPEKHFKKYMYAAKFVQMVKAKTPKI 581

  Fly   503 TYFSTLGKCQLMETMTDFEIRFYSGAK-LLKTPSEGLKVYDRNGMLLSDYSCSESRSLI-----E 561
            |.:|...|||||||:.|:|:.||...| :|.:.:..:|:.|.:|.:   |...||.|.|     .
Mosquito   582 TLYSDKAKCQLMETLQDYEVVFYDDTKIILSSTNNEIKMIDGSGKV---YRGLESISAINITYLH 643

  Fly   562 HGNECFTHCVNISNALEVAQTKDNSCFPVTIGRR 595
            |..|...||..|...|... :.....|||.||||
Mosquito   644 HFQETREHCHRIEKMLSTV-SYSGKTFPVIIGRR 676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SAK	NP_649324.1	STKc_PLK4	12..267	CDD:271088	172/254 (68%)
		POLO_box_Plk4_1	382..497	CDD:240557	56/115 (49%)
		POLO_box_Plk4_2	498..596	CDD:240558	40/104 (38%)
		POLO_box_Plk4_3	657..738	CDD:240559
LOC1268576	XP_061497547.1	None